59971-16-3

Basic information

• Product Name: 25-deoxy-20-hydroxyecdyson-26-oic acid
• Synonyms: 25-deoxy-20-hydroxyecdyson-26-oic acid
• CAS NO: 59971-16-3
• Molecular Weight: 494.626
• Mol File: 59971-16-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 25-deoxy-20-hydroxyecdyson-26-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 25-deoxy-20-hydroxyecdyson-26-oic acid(59971-16-3)
• EPA Substance Registry System: 25-deoxy-20-hydroxyecdyson-26-oic acid(59971-16-3)

Safety Data

• Hazardous Substances Data: 59971-16-3(Hazardous Substances Data)

Upstream product

• 13408-48-5 ponasterone A 

Relevant articles and documents

ECDYSTEROID METABOLISM IN A CRAB: CARCINUS MAENAS L.

Ponasterone A (25-deoxy-20-hydroxyecdysone) and 20-hydroxyecdysone were the major ecdysteroids detected in crab hemolymph, although some ecdysone was also present.The metabolism of ponasterone A was examined in intermolt and premolt crabs either by injecting the radiolabeled hormone or by incubating tissues in its presence.Metabolites were extracted from the surrounding seawater and from tissues and separated by high-performance liquid chromatography.Ponasterone A metabolism proceeds through (1) C-25 and C-26 hydroxylation, followed by formation of inactivation products via oxidation of the terminal alcoholic group to a carboxylic residue, (2) conjugation, (3) binding to very polar compounds and (4) side-chain scission.The conversion of ponasterone A into 20-hydroxyecdysone, inokosterone (25-deoxy-20,26-dihydroxyecdysone), 20,26-dihydroxyecdysone and ecdysonoic acids, as well as the formation of conjugates and of very polar compounds, occurs in various tissues.These metabolites were excreted by both intermolt and premolt crabs.