60037-42-5

Basic information

• Product Name: 4-(2-Acetoxy-ethyl)phenyl Acetate
• Synonyms: 4-(2-Acetoxy-ethyl)phenyl Acetate
• CAS NO: 60037-42-5
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.23716
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 60037-42-5.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane, Ethyl Acetate, Methanol, Hexane
• CAS DataBase Reference: 4-(2-Acetoxy-ethyl)phenyl Acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Acetoxy-ethyl)phenyl Acetate(60037-42-5)
• EPA Substance Registry System: 4-(2-Acetoxy-ethyl)phenyl Acetate(60037-42-5)

Safety Data

• Hazardous Substances Data: 60037-42-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Oil

Uses

Tyrosol (T947800) derivative, phenolic antioxidant.

Upstream product

• 501-94-0 p-hydroxyphenethyl alcohol 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 141-78-6 ethyl acetate 
• 156-38-7 4-hydroxyphenylacetate 
• 108-22-5 Isopropenyl acetate 
• 73823-79-7 β-(4-acetylphenyl)ethyl acetate 
• 103-45-7 acetic acid phenethyl ester 
• 60-12-8 2-phenylethanol 
• 155164-63-9 2-acetyl-4,5-dichloropyridazin-3(2H)-one 
• 108-05-4 vinyl acetate 
• 94414-03-6 4-[2-(acetyloxy)ethyl]-4-hydroxy-2,5-cyclohexadien-1-one 
• 60759-49-1 N-acetyl-1,3-oxazol-2-one 
• 107866-54-6 1-acetyl-1H-1,2,3-triazolo<4,5-b>pyridine 

Downstream Products

• 58556-55-1 2-(4-hydroxyphenyl)ethyl acetate 
• 501-94-0 p-hydroxyphenethyl alcohol 

Relevant articles and documents

Synthesis method of p-hydroxyphenethyl alcohol

The invention discloses a method for synthesizing p-hydroxyphenethyl alcohol from phenethyl alcohol as a raw material. The method comprises the steps as follows: firstly, phenethyl alcohol and acid anhydride are subjected to an esterification reaction to obtain phenethyl alcohol ester; then, phenethyl alcohol ester and acid anhydride are subjected to an electrophilic substitution reaction under the action of a catalyst and a catalyst promoter to obtain 4-acryl phenethyl alcohol ester; next, 4-acryl phenethyl alcohol ester and hydrogen peroxide are subjected to a Baeyer-Villiger oxidation reaction under the action of organic acid and an oxidation catalyst to obtain 4-acyloxy phenethyl alcohol ester; finally, the 4-acyloxy phenethyl alcohol ester is subjected to a hydrolysis reaction in alkaline water to obtain p-hydroxyphenethyl alcohol. The process for synthesizing p-hydroxyphenethyl alcohol has the advantages that raw materials are widely sourced, the yield is high, the process is concise, few three wastes are produced and industrialization is easy to realize.

TiCl4/Et3N-Mediated Condensation of Acetate and Formate Esters: Direct Access to β-Alkoxy- and β-Aryloxyacrylates

A methodology to build (E)-β-alkoxy- and (E)-β-aryloxyacrylate moieties from acetate and formate esters promoted by the TiCl4/Et3N system is presented. The reaction is compatible with a broad range of structural skeletons and elapses through an unusual condensation pathway. Taking into account the obtained results, we propose a plausible mechanism involving a bimetallic titanium intermediate for this type of transformation.

Solventless acetylation of alcohols and phenols catalyzed by supported iron oxide nanoparticles

Supported iron oxide nanoparticles on silicate catalysts were found to be efficient and easily recoverable materials in the acetylation of alcohols and phenols to their corresponding acetyl compounds using acetic anhydride under mild and solvent-less conditions. The supported iron oxide nanoparticles could be easily recovered from the reaction mixture and reused ten times without any loss in activity.