60049-83-4

Basic information

• Product Name: Benzenamine, 4-methoxy-N,N-dimethyl-2-nitro-
• Synonyms: Benzenamine,4-methoxy-N,N-dimethyl-2-nitro;4-(dimethylamino)-3-nitroanisole;4-methoxy-N,N-dimethyl-2-nitrobenzenamine;N,N-Dimethyl-4-methoxy-2-nitro-anilin;N,N-dimethyl-4-methoxy-2-nitro-aniline;N,N-dimethyl-2-nitro-p-anisidine;N,N-dimethyl-2-nitro-4-methoxyaniline;4-Methoxy-2-nitro-N,N-dimethylbenzeneamine
• CAS NO: 60049-83-4
• Molecular Formula: C9H12N2O3
• Molecular Weight: 196.206
• Mol File: 60049-83-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-methoxy-N,N-dimethyl-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-methoxy-N,N-dimethyl-2-nitro-(60049-83-4)
• EPA Substance Registry System: Benzenamine, 4-methoxy-N,N-dimethyl-2-nitro-(60049-83-4)

Safety Data

• Hazardous Substances Data: 60049-83-4(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 7647-01-0 hydrogenchloride 
• 701-56-4 4-methoxy-N,N-dimethylanilne 
• 77-78-1 dimethyl sulfate 
• 96-96-8 4-methoxy-2-nitroaniline 
• 104-94-9 4-methoxy-aniline 
• 74-88-4 methyl iodide 
• 544-16-1 n-Butyl nitrite 

Downstream Products

• 1034887-04-1 N-(2-dimethylamino-5-methoxyphenyl)acetamide 
• 149156-04-7 1-(2-Dimethylamino-5-methoxy-phenyl)-3-pentyl-urea 
• 183251-91-4 4-methoxy-N¹,N¹-dimethyl-o-phenylenediamine 

Relevant articles and documents

FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE

A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula (I), wherein the variables are described throughout the application.

Transnitrosation by N-aryl-N-nitrosoureas; NO-carrying O-nitrosoisourea

Transfer of nitroso groups, so-called transnitrosation, from aromatic N-nitroso compounds such as N-nitrosoureas, N-nitrosamides and N-nitrosamines, to aromatic amines or ureas was observed under non-acidic conditions at room temperature. Sterically hindered 3,3-dibenzyl-1-(4-tolyl)-1-nitrosourea (1a) rapidly nitrosates indoline, N-alkylanilines or 3-methyl-1-(4-tolyl)urea to give their N-nitroso derivatives. In the case of N,N-dimethylanilines, nitrosative demethylation occurs to give N-methyl-N-nitrosanilines. The transnitrosation is accelerated by electron-releasing groups on the nitroso acceptors, N-alkylanilines. The transnitrosation mechanism is considered to be as follows: N-nitrosourea (1) thermally decomposes to nitric oxide and ureidyl radical followed by formation of an O-nitrosoisourea intermediate (10), which acts as an NO-carrying agent and nitrosates anilines or ureas.

AROMATIC TERTIARY AMINES AND n-BUTYL NITRITE

The reaction between alkyl nitrites, particularly n-butyl nitrite, and tertiary aromatic amines under a variety of experimental conditions promptly yielded products of N-dealkylation-N-nitrosation, ring nitration, ipso-substitution and, occasionally, combinations of these processes.Aminoethers were detected as final products and intermediates on the way to N-nitrosations.Reaction pathways are suggested for some of the observed behaviours on the basis of experimental evidences whereas other alternatives are discarded.