601-77-4

Basic information

• Product Name: N-NITROSO-DI-ISO-PROPYLAMINE
• Synonyms: n-nitroso-diisopropylamin;N-Nitrosodi-i-propylamine;, N-isopropyl-N-nitroso-2-propanamine;1,1'-Dimethyl-N-nitrosodiethylamine;N-(1-Methylethyl)-N-nitroso-2-propanamine;NSC 336;Diisopropylnitrosoamine;N,N-di(propan-2-yl)nitrous amide
• CAS NO: 601-77-4
• Molecular Formula: C₆H₁₄N₂O
• Molecular Weight: 130.18816
• Product Categories: Nitrosamine;Mutagenesis Research Chemicals;Nitric Oxide Reagents
• Mol File: 601-77-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300°C
• Boiling Point: 194.5℃
• Flash Point: 73.6°C
• Appearance: /
• Density: 0.9422
• Vapor Pressure: 0.616mmHg at 25°C
• Refractive Index: 1.4431 (estimate)
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• PKA: -2.65±0.70(Predicted)
• Water Solubility: 13.02g/L(24 oC)
• CAS DataBase Reference: N-NITROSO-DI-ISO-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-NITROSO-DI-ISO-PROPYLAMINE(601-77-4)
• EPA Substance Registry System: N-NITROSO-DI-ISO-PROPYLAMINE(601-77-4)

Safety Data

• Statements: 22-45
• Safety Statements: 53
• RIDADR: 2811
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 601-77-4(Hazardous Substances Data)

Usage

Description

N-NITROSO-DI-ISO-PROPYLAMINE is a nitroso compound that exhibits carcinogenic effects.

Uses

Used in Research and Development:
N-NITROSO-DI-ISO-PROPYLAMINE is used as a research chemical for studying the carcinogenic properties of nitroso compounds. Its application in this field aids scientists in understanding the mechanisms of carcinogenesis and developing potential countermeasures or treatments.
Used in Regulatory Compliance and Testing:
N-NITROSO-DI-ISO-PROPYLAMINE is utilized in regulatory compliance and testing to ensure the safety of consumer products and industrial materials. By testing for the presence of this compound, industries can adhere to safety standards and protect the public from exposure to harmful substances.
Used in Environmental Monitoring:
N-NITROSO-DI-ISO-PROPYLAMINE is used in environmental monitoring to detect and quantify the presence of carcinogenic nitroso compounds in air, water, and soil. This helps in assessing the environmental impact of pollutants and implementing measures to mitigate their effects.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS and AMINES.

InChI:InChI=1/C6H14N2O/c1-5(2)8(7-9)6(3)4/h5-6H,1-4H3

Upstream product

• 543-67-9 n-propyl nitrite 
• 108-18-9 diisopropylamine 
• 80-11-5 N-methyl-N-nitrosotoluene-p-sulfonamide 
• 19009-39-3 N,N-diisopropylcarbamoyl chloride 
• 75-05-8 acetonitrile 
• 7782-77-6 cis-nitrous acid 
• 75-31-0 isopropylamine 

Downstream Products

• 921-14-2 N,N-diisopropylhydrazine 
• 4164-30-1 diisopropylnitramine 
• 3298-51-9 N,N-Diisopropyl-N'-formyl-hydrazin 
• 13304-31-9 Tetra-isopropyl-2-tetrazen 
• 36909-82-7 2-Benzolsulfonyl-1,1-diisopropyl-hydrazin 
• 18481-95-3 1,1-diisopropyl-4-phenyl thiosemicarbazide 
• 128190-41-0 1-(4-Nitrophenyl)glyoxal-1-diisopropylhydrazon 
• 112080-82-7 4-Nitrobenzaldehyd-diisopropylhydrazon 
• 88858-81-5 5-Nitro-2-hydroxy-benzal-diisopropylhydrazin 
• 108-18-9 diisopropylamine 

Relevant articles and documents

Reactivity of Nucleophilic Nitrogen Compounds towards the Nitroso Group

We discuss the reactivity of 43 nucleophilic nitrogen compounds towards the nitroso group of N-methyl-N-nitrosotoluene-p-sulfonamide (MNTS), and in some cases with alkyl nitrites.The series of nucleophiles considered is structurally very varied, includes members exhibiting the alpha effect, and covers 8 pKa units and a range of reactivities of almost five orders of magnitude.The values of solvent isotope effects and activation parameters have been measured and throw light on the structure of the transition states involved.Reactivities do not correlate well with thebasicity of the nucleophile, largely owing to the behaviour of primary amines, ammonia and nucleophiles with an alpha effect.Application of the curve crossing model suggests a relationship with vertical ionization potentials.The relationship with Ritchie's N+ scale is discussed, and interesting correlations with the reactivities of the same nucleophiles in various other chemical processes are noted.