602-64-2 Usage
Description
ANTHRACENE BROWN is a trihydroxyanthraquinone with the chemical formula C14H8O4. It is a brown powder that is soluble in alcohol, ether, and glacial acetic acid, slightly soluble in water and chloroform, and sublimates at 290°C. It is also known as Anthragallol and is the most active inhibitor against xanthine oxidase.
Uses
Used in Pharmaceutical Industry:
ANTHRACENE BROWN is used as an active pharmaceutical ingredient for its inhibitory effects against xanthine oxidase, which can be beneficial in the treatment of various diseases and conditions related to the enzyme.
Used in Dye Industry:
ANTHRACENE BROWN is used as a dye due to its dark brown color. It can be used in the production of various colored products, such as textiles, plastics, and paints.
Used in Chemical Industry:
ANTHRACENE BROWN is used as a chemical intermediate in the synthesis of other compounds and materials.
Properties and Applications:
ANTHRACENE BROWN exhibits good ironing fastness, light fastness, fulling, perspiration fastness, soaping, and resistance to water, alkali, and acid, making it suitable for various applications in different industries.
Standard:
The standard for ANTHRACENE BROWN includes the following ratings:
Ironing Fastness: ISO 5, AATCC Dry 3, wet 5
Light Fastness: ISO 5-6, AATCC 5
Fulling: ISO 3-4
Perspiration Fastness: ISO 2-3
Soaping: ISO 5
Water: ISO 5
Alkali: ISO 5
Acid: ISO 4
Preparation
Commonly known as ?Anthragallol. (A)3,4,5-Trihydroxybenzoic acid and Benzoic acid and sulfuric acid heated; (b) in the presence of zinc chloride, heating gallic acid and Phthalic anhydride; (c) 2-Hydroxy-1,3-dinitroanthraquinone?reduction in strong alkaline solution; (d)1,3-Diamino-2-hydroxyanthracene-9,10-dione and hydrochloric acid heated under pressure.
Note: The product is a free acid state paste; powdery product is sodium
Standard
Ironing Fastness
Alkali
Acid
ISO
5
AATCC
Dry 3,wet 5
Check Digit Verification of cas no
The CAS Registry Mumber 602-64-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 602-64:
(5*6)+(4*0)+(3*2)+(2*6)+(1*4)=52
52 % 10 = 2
So 602-64-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H8O5/c15-9-5-8-10(14(19)13(9)18)12(17)7-4-2-1-3-6(7)11(8)16/h1-5,15,18-19H
602-64-2Relevant articles and documents
An anthraquinone scaffold for putative, two-face bim BH3 α-helix mimic
Zhang, Zhichao,Li, Xiangqian,Song, Ting,Zhao, Yan,Feng, Yingang
, p. 10735 - 10741 (2013/02/23)
Bim BH3 peptide features an α-helix with hotspot residues on multiple faces. Compound 5 (6-bromo-2,3-dihydroxyanthracene-9,10-dione), which adopts a rigid-plan amphipathic conformation, was designed and evaluated as a scaffold to mimic two faces of Bim α-helix. It reproduced the functionalities of both D67 and I65 on two opposing helical sides. Moreover, it maintained the two-faced binding mode during further evolution. A putative BH3 α-helix mimic and nanomolar Bcl-2/Mcl-1 dual inhibitor, 6, was obtained based on the structure of 5.
Novel anthraquinones and process for the preparation and method of use thereof
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Page/Page column 5, (2008/06/13)
A process for the preparation of hydroxyl substituted anthraquinones is described. The process couples a phthalic anhydride (substituted or unsubstituted) to benzene ring moiety substituted with at least two hydroxyl groups. Remaining hydroxy groups were converted to methoxy groups in some anthraquinones. The compounds are particularly useful for the treatment of parasitic diseases. Also, a method of treating or preventing malaria, filariasis schistosomiasis and other parasitic diseases using anthraquinones.