603-10-1

Basic information

• Product Name: 2,3,6-TRINITROPHENOL
• Synonyms: 2,3,6-TRINITROPHENOL;2,3,6-trinitrophenol moistened with water (H2O ~40%);2,3,6-TRINITROPHENOL (WITH 0,4 ML H2O/G);2,3,6-Trinitrophenol moistened with water, >=95.0% (calc. based on dry substance, HPLC)
• CAS NO: 603-10-1
• Molecular Formula: C₆H₃N₃O₇
• Molecular Weight: 229.1
• EINECS: 201-865-9
• Product Categories: Organic Building Blocks;Oxygen Compounds;Phenols
• Mol File: 603-10-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 119-120 °C(lit.)
• Boiling Point: 337.9°C at 760 mmHg
• Flash Point: 151.1°C
• Appearance: /
• Density: 1.856g/cm³
• Vapor Pressure: 5.2E-05mmHg at 25°C
• Refractive Index: 1.701
• CAS DataBase Reference: 2,3,6-TRINITROPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,6-TRINITROPHENOL(603-10-1)
• EPA Substance Registry System: 2,3,6-TRINITROPHENOL(603-10-1)

Safety Data

• Hazard Codes: F,T
• Statements: 1-4-11-24/25
• Safety Statements: 7-16-35-45
• RIDADR: UN 1344 4.1/PG 1
• WGK Germany: 3
• Hazardous Substances Data: 603-10-1(Hazardous Substances Data)

Usage

Uses

2,3,6-Trinitrophenol is a useful reactant and reagent in organic reactions.

InChI:InChI=1/C6H3N3O7/c10-6-4(8(13)14)2-1-3(7(11)12)5(6)9(15)16/h1-2,10H

Synthetic route

2,5-dinitrophenol (329-71-5) → styphnic acid (82-71-3) + 2,4,5-trinitrophenol (610-26-4) + 2,3,6-trinitrophenol (603-10-1)

Conditions	Yield
beim Nitrieren;

2,3-dinitrophenol (66-56-8) → styphnic acid (82-71-3) + 2,3,6-trinitrophenol (603-10-1)

Conditions	Yield
beim Nitrieren;
beim Nitrieren;

2,3-dinitrophenol (66-56-8) → 2,3,6-trinitrophenol (603-10-1)

4-amino-2,3,6-trinitrophenol → 2,3,6-trinitrophenol (603-10-1)

Conditions	Yield
bei der Diazotierung und nachflgenden Behandlung mit Alkohol;

2,5-dinitrophenol (329-71-5) → 2,3,6-trinitrophenol (603-10-1) + 2.4.5-trinitro-phenol, 2.4.6-trinitro-resorcinol

Conditions	Yield
beim Nitrieren;

meta-nitrophenol (554-84-7) → 2,3,6-trinitrophenol (603-10-1)

Conditions	Yield
Multi-step reaction with 2 steps 1: durch Nitrieren 2: beim Nitrieren View Scheme

diazomethane (186581-53-3, 908094-01-9) + 2,3,6-trinitrophenol (603-10-1) → 2,3,6-Trinitroanisole (88106-08-5)

Conditions	Yield
In diethyl ether for 2h; Ambient temperature;	95%

2,3,6-trinitrophenol (603-10-1) → styphnic acid (82-71-3)

Conditions	Yield
With nitric acid

2,3,6-trinitrophenol (603-10-1) + nitric acid (7697-37-2) → styphnic acid (82-71-3)

Upstream product

• 329-71-5 2,5-dinitrophenol 
• 554-84-7 meta-nitrophenol 
• 66-56-8 2,3-dinitrophenol 

Downstream Products

• 82-71-3 styphnic acid