60522-08-9

Basic information

• Product Name: tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate
• Synonyms: tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate
• CAS NO: 60522-08-9
• Molecular Weight: 327.445
• Mol File: 60522-08-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate(60522-08-9)
• EPA Substance Registry System: tert-butyl 3-methyl-2-(4-methylphenylsulfonamido)butanoate(60522-08-9)

Safety Data

• Hazardous Substances Data: 60522-08-9(Hazardous Substances Data)

Upstream product

• 17360-25-7 N-(p-toluenesulfonyl)-L-valine 
• 115-11-7 isobutene 
• 13518-40-6 L-valine tert-butylester hydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 13211-31-9 tert-butyl L-valinate 
• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 60522-09-0 (S)-3-Methyl-2-[methyl-(toluene-4-sulfonyl)-amino]-butyric acid tert-butyl ester 
• 245364-77-6 2-[benzyl-(toluene-4-sulfonyl)-amino]-3-methyl-butyric acid tert-butyl ester 
• 245364-83-4 3-methyl-2-[(4-methyl-benzyl)-(toluene-4-sulfonyl)-amino]-butyric acid tert-butyl ester 
• 245364-80-1 2-[(4-chloro-benzyl)-(toluene-4-sulfonyl)-amino]-3-methyl-butyric acid tert-butyl ester 
• 270072-05-4 N-4-toluene-sulfonyl-N-benzyl-L-valine 
• 245365-06-4 N-benzyloxy-2-[benzyl-(toluene-4-sulfonyl)-amino]-3-methyl-butyramide 
• 245365-12-2 N-benzyloxy-3-methyl-2-[(4-methyl-benzyl)-(toluene-4-sulfonyl)-amino]-butyramide 
• 245365-09-7 N-benzyloxy-2-[(4-chloro-benzyl)-(toluene-4-sulfonyl)-amino]-3-methyl-butyramide 
• 60522-10-3 (S)-3-methyl-2-(N-methyl-N-tosylamino)butanoic acid 
• 124312-59-0 (S)-3,N-Dimethyl-2-[methyl-(toluene-4-sulfonyl)-amino]-butyramide 
• 60522-11-4 (S)-3-Methyl-2-[methyl-(toluene-4-sulfonyl)-amino]-butyric acid; compound with dicyclohexyl-amine 

Relevant articles and documents

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents

Polymer-supported reagents and sequestering agents may be used to generate an array of variously substituted hydroxamic acid derivatives as potential inhibitors of matrix metalloproteinases without any chromatographic purification step.