60633-91-2Relevant articles and documents
Intracellular Generation of a Diterpene-Peptide Conjugate that Inhibits 14-3-3-Mediated Interactions
Parvatkar, Prakash,Kato, Nobuo,Uesugi, Motonari,Sato, Shin-Ichi,Ohkanda, Junko
, p. 15624 - 15627 (2015)
Synthetic agents that disrupt intracellular protein-protein interactions (PPIs) are highly desirable for elucidating signaling networks and developing new therapeutics. However, designing cell-penetrating large molecules equipped with the many functional
A Highly Fluorinated Chiral Aldehyde for Enantioselective Fluorescent Recognition in a Biphasic System
Wang, Chao,Wu, Xuedan,Pu, Lin
, p. 10749 - 10752 (2017)
A 1,1′-bi-2-naphthol (BINOL)-based aldehyde containing four perfluoroalkyl groups has been designed and synthesized. It shows enantioselective fluorescence enhancement at 420 nm when treated with the enantiomers of trans-1,2-diaminocyclohexane in an organ
Compound with PPAR delta agonistic activity, pharmaceutical composition and medical application
-
Paragraph 0061-0065, (2021/03/13)
The invention discloses a compound with PPAR delta agonistic activity, a pharmaceutical composition and medical application, wherein the structure of the compound is shown as a formula I in the specification. The compound shown in the formula I is a novel
An Intramolecular Cycloaddition Approach to the Kauranoid Family of Diterpene Metabolites
Callebaut, Brenda,Hullaert, Jan,Van Hecke, Kristof,Winne, Johan M.
supporting information, p. 310 - 314 (2019/01/10)
Synthetic studies toward the ent-kauranoid family of diterpene natural products are reported. An intramolecular (4 + 3) cycloaddition allows the direct elaboration of diverse natural product frameworks, encompassing a challenging bicyclo[3.2.1]octane core. The established routes comprise only a few synthetic operations (3-5 steps), transforming a range of simple starting materials into the tetracyclic scaffolds that are commonly found in many ent-kaurene metabolites.