606968-05-2 Usage
Description
Methylene-Bis Paroxetine Dihydrochloride, also known as Paroxetine EP Impurity F, is a chemical compound derived from Paroxetine, a selective serotonin reuptake inhibitor (SSRI) commonly used as an antidepressant. It is characterized by its ability to act as a chiral reference substance in analytical methods.
Uses
Used in Pharmaceutical Industry:
Methylene-Bis Paroxetine Dihydrochloride is used as a chiral reference substance for the chiral purity determination of Paroxetine drug substance. This application is crucial in ensuring the quality, safety, and efficacy of Paroxetine-based medications, as it helps to identify and quantify the presence of impurities that may affect the drug's performance.
Used in Chiral HPLC Method:
Methylene-Bis Paroxetine Dihydrochloride is utilized in the chiral high-performance liquid chromatography (HPLC) method for the analysis and determination of the enantiomeric purity of Paroxetine. This method is essential in the pharmaceutical industry to guarantee the consistency and reliability of Paroxetine medications, as well as to comply with regulatory requirements for drug quality and purity.
Check Digit Verification of cas no
The CAS Registry Mumber 606968-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,6,9,6 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 606968-05:
(8*6)+(7*0)+(6*6)+(5*9)+(4*6)+(3*8)+(2*0)+(1*5)=182
182 % 10 = 2
So 606968-05-2 is a valid CAS Registry Number.
606968-05-2Relevant articles and documents
Method for preparing paroxetine impurity
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Paragraph 0050; 0051, (2017/08/29)
The invention provides a method for preparing paroxetine impurity. The method comprises the following steps: putting paroxetine or salt thereof into a reaction solvent, reacting with aldehyde solution in an acidic system and then separating, thereby acquiring a target product 4,4'-methylene paroxetine biopolymer. The method for preparing paroxetine impurity provided by the invention has the advantages of simple operation, high product yield, high purity and low cost.
