611-60-9 Usage
Description
Thymidine 5-(tetrahydrogen triphosphate), 3-deoxyis a pyrimidine 2',3'-dideoxyribonucleoside 5'-triphosphate with thymine as the nucleobase. It is a key component in the field of molecular biology and has various applications in different industries.
Uses
Used in Molecular Biology:
Thymidine 5-(tetrahydrogen triphosphate), 3-deoxyis used as a building block for the synthesis of DNA. It plays a crucial role in the process of DNA replication, as it helps in the formation of the DNA strand by providing the necessary thymine nucleotide.
Used in Diagnostics:
In the diagnostics industry, Thymidine 5-(tetrahydrogen triphosphate), 3-deoxyis used as a marker in various molecular techniques, such as polymerase chain reaction (PCR) and DNA sequencing. It aids in the detection and identification of specific DNA sequences, contributing to the accurate diagnosis of genetic disorders and diseases.
Used in Research and Development:
Thymidine 5-(tetrahydrogen triphosphate), 3-deoxyis used as a research tool in the development of new drugs and therapies targeting DNA-related processes. Its unique properties make it valuable for studying the mechanisms of DNA replication, repair, and mutagenesis, which can lead to the discovery of novel therapeutic approaches.
Used in Biotechnology:
In the biotechnology industry, Thymidine 5-(tetrahydrogen triphosphate), 3-deoxyis employed in the synthesis of modified DNA molecules for various applications, such as the development of new vaccines, gene therapy, and the creation of genetically modified organisms (GMOs) for agricultural and industrial purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 611-60-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 611-60:
(5*6)+(4*1)+(3*1)+(2*6)+(1*0)=49
49 % 10 = 9
So 611-60-9 is a valid CAS Registry Number.
611-60-9Relevant articles and documents
Anti-retroviral agents and delivery systems for the same
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, (2008/06/13)
The present invention provides a method for preventing or treating disease caused by retroviruses, particularly human immunodeficiency virus. Liposomes are prepared containing phosphorylated derivatives of nucle-osides which act as chain-terminators of viral DNA. The phosphorylated nucleosides perse, without encapsulation in liposomes, do not readily enter cells. However, they are found to be effective if encapsulated in liposomes because they remain in liposomes longer, they do not escape easily from cells, and they constitute the active form for incorporation in viral DNA chains. When administered to a host, the liposomes are taken up by endocytic and phagocytic cells, which are important reservoirs of HIV infection. If coated with an appro-priate ligand, such as an immunoglobulin molecule, lipo-somes containing the phosphorylated nucleosides can be directed to phagocytic cells, CD4-positive cells, or infected host cells.
A novel phosphorylating agent, P-diphenyl, P'-morpholinopyrophosphorochloridate.
IKEHARA,OHTSUKA
, p. 997 - 999 (2007/10/04)
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