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613-70-7

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613-70-7 Usage

Description

2-METHOXYPHENYL ACETATE is an organic compound with a distinct aromatic profile, characterized by its woody, guaiacol, smoky, astringent, and phenolic taste with vanillin and coumarin nuances. It is synthesized from guaiacol and excess acetic anhydride in the presence of trace amounts of H2SO4 and has an odor similar to that of guaiacol.

Uses

Used in Flavor and Fragrance Industry:
2-METHOXYPHENYL ACETATE is used as a flavoring agent for its woody, guaiacol, smoky, astringent, and phenolic taste characteristics, which can enhance the flavor profile of various food and beverage products.
2-METHOXYPHENYL ACETATE is also used as a fragrance ingredient for its unique aroma, which can add depth and complexity to perfumes and other scented products.
Used in Chemical Synthesis:
2-METHOXYPHENYL ACETATE can be used as a starting material or intermediate in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and other specialty chemicals, due to its versatile chemical structure and reactivity.
Used in Research and Development:
2-METHOXYPHENYL ACETATE can be employed as a research tool in the study of chemical reactions, mechanisms, and the development of new synthetic methods, as well as in the investigation of its potential applications in various fields, such as materials science, pharmaceuticals, and biotechnology.

Preparation

From guaiacol and excess acetic anhydride in the presence of trace amounts of H2SO4.

Check Digit Verification of cas no

The CAS Registry Mumber 613-70-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 613-70:
(5*6)+(4*1)+(3*3)+(2*7)+(1*0)=57
57 % 10 = 7
So 613-70-7 is a valid CAS Registry Number.
InChI:InChI=1S/C9H10O3/c1-7(10)12-9-6-4-3-5-8(9)11-2/h3-6H,1-2H3

613-70-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxyphenyl Acetate

1.2 Other means of identification

Product number -
Other names Phenol, 2-methoxy-, acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:613-70-7 SDS

613-70-7Relevant articles and documents

Synthesis of a TNF inhibitor, flurbiprofen and an: I -Pr analogue in enantioenriched forms by copper-catalyzed propargylic substitution with Grignard reagents

Isogawa, Yukari,Kobayashi, Yuichi,Ogawa, Narihito,Takashima, Yuji,Tsuboi, Atsuki

supporting information, p. 9906 - 9909 (2021/12/07)

The copper-catalyzed substitution reaction of diethyl phosphate derived from TMSCCCH(OH)CH2CH2OTBDPS with 3-c-C5H9-4-MeOC6H3MgBr, followed by several transformations, afforded a tumor necrosis factor inhibitor possessing a Ph-acetylene moiety. The inhibitor was also synthesized from phenylacetylene phosphate PhCCCH(OP(O)(OEt)2)CH2CH2OTBDPS. Furthermore, the substitution of phosphates derived from TMSCCCH(OH)CH3 and TMSCCCH(OH)-i-Pr with 3-F-4-PhC6H3MgBr gave the corresponding substitution products, which were transformed to flurbiprofen and its i-Pr analogue, respectively. The copper-catalyzed substitutions in these syntheses proceeded in a regio- and stereoselective manner. This journal is

Methods for preparation of apremilast

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Page/Page column 20-21, (2021/05/19)

The present invention discloses a method for preparation of Apremilast. β-phthalimino vinylsulfones are reacted through the asymmetric addition reaction to form an addition product, and the drug of Apremilast can be obtained from the addition product through simple reactions. The method is a process for synthesizing Apremilast in a more efficient way.

Method for promoting acylation of amine or alcohol by carbon dioxide

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Paragraph 0034-0035, (2021/05/29)

The invention relates to a method for promoting acylation of amine or alcohol by carbon dioxide, which comprises the following steps of: mixing an amine compound, carboxylate or thiocarboxylate compound and a reaction solvent under the action of carbon dioxide, and reacting to obtain an amide compound, or under the action of carbon dioxide, mixing the alcohol compound, the thiocarboxylate compound and the reaction solvent [gamma]-valerolactone, and reacting to obtain the ester compound. According to the invention, under the promotion action of carbon dioxide, carboxylate or thiocarboxylate is used as an acylation reagent, and amine and alcohol are converted into amide and ester compounds in the absence of a transition metal catalyst, so that acylation reagents such as acyl chloride or anhydride with irritation and corrosivity are avoided; and the method has the advantages of simple operation, mild reaction conditions, high tolerance of substrate functional groups, strong applicability and high yield, and provides an efficient, reliable and economical preparation method for synthesis of amide and ester compounds.

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