613-88-7

Basic information

• Product Name: DL-MANDELONITRILE
• Synonyms: DL-MANDELONITRILE;Ai3-50437;Benzaldehydkyanhydrin [czech]
• CAS NO: 613-88-7
• Molecular Formula: C₈H₇NO
• Molecular Weight: 133.14728
• Mol File: 613-88-7.mol
• Article Data: 153

Chemical Properties

• Melting Point: 22°C
• Boiling Point: 245.66°C (rough estimate)
• Appearance: /
• Density: 1.1165
• Refractive Index: 1.5282 (estimate)
• CAS DataBase Reference: DL-MANDELONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-MANDELONITRILE(613-88-7)
• EPA Substance Registry System: DL-MANDELONITRILE(613-88-7)

Safety Data

• Hazardous Substances Data: 613-88-7(Hazardous Substances Data)

Upstream product

• 10425-22-6 Benzil dicyanohydrin 
• 64-17-5 ethanol 
• 100-52-7 benzaldehyde 
• 74-90-8 hydrogen cyanide 
• 151-50-8 potassium cyanide 
• 143-33-9 sodium cyanide 
• 134-81-6 benzil 
• 29883-15-6 amygdalin 
• 613-90-1 benzoyl cyanide 
• 25438-37-3 phenyl(trimethylsiloxy)acetonitrile 
• 108-24-7 acetic anhydride 
• 4657-12-9 sodium hydroxy(phenyl)methanesulfonate 
• 99-35-4 1,3,5-trinitrobenzene 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 5766-79-0 2-phenyl-2-piperidinoacetonitrile 
• 4242-46-0 1-cyanobenzyl benzoate 
• 16183-45-2 1-hydroxy-1-phenylbutan-2-one 
• 39531-24-3 5-methyl-3-phenyl-1-benzofuran-2(3H)-one 
• 17064-16-3 2-(benzo[d][1,3]dioxol-5-yl)-5-phenyloxazole 
• 6974-51-2 2-(naphthalen-1-yl)-2-phenylacetonitrile 
• 58258-48-3 2-([1,1′-biphenyl]-4-yl)-2-phenylacetonitrile 
• 41049-36-9 1-hydroxy-1,3-diphenylacetone 
• 6830-78-0 3,6-diphenyl-1,2,4,5-tetrazine 
• 22259-83-2 2-chloro-2-phenylacetonitrile 
• 1088-34-2 3,6-diphenylpyrazin-2(1H)-one 
• 17199-29-0 (S)-Mandelic acid 
• 56946-79-3 bis-(2-chloro-2-phenyl-acetylamino)-phenyl-methane 
• 90-63-1 (RS)-1-hydroxy-1-phenylpropan-2-one 

Relevant articles and documents

CO2-Enabled Cyanohydrin Synthesis and Facile Iterative Homologation Reactions**

Thermodynamic and kinetic control of a chemical process is the key to access desired products and states. Changes are made when a desired product is not accessible; one may manipulate the reaction with additional reagents, catalysts and/or protecting groups. Here we report the use of carbon dioxide to accelerate cyanohydrin synthesis under neutral conditions with an insoluble cyanide source (KCN) without generating toxic HCN. Under inert atmosphere, the reaction is essentially not operative due to the unfavored equilibrium. The utility of CO2-mediated selective cyanohydrin synthesis was further showcased by broadening Kiliani–Fischer synthesis under neutral conditions. This protocol offers an easy access to a variety of polyols, cyanohydrins, linear alkylnitriles, by simply starting from alkyl- and arylaldehydes, KCN and an atmospheric pressure of CO2.

CO2-Mediated Non-Destructive Cyanide Wastewater Treatment

The facile removal of cyanide anions from cyanide-containing water was achieved using CO2 in conjunction with aldehydes which can be recycled from the process. The conversion of the cyanide ion into an insoluble cyanohydrin in water allowed the removal of cyanide and could be used as a method for treating cyanide contaminated wastewater and for recovering cyanide or cyanohydrins for further applications.

Constructing a triangular metallacycle with salen-Al and its application to a catalytic cyanosilylation reaction

A triangular metallosalen-based metallacycle was constructed in quantitative yield by the self-assembly of a 180° bis(pyridyl)salen-Al complex and a 60° diplatinum(ii) acceptor in a 1?:?1 stoichiometric ratio. This metallacycle was then successfully used to cyanosilylate a wide range of benzaldehydes with trimethylsilyl cyanide.