613-93-4 Usage
Description
N-METHYLBENZAMIDE, also known as methyl benzoate amide, is an organic compound with the chemical formula C8H9NO. It is a white crystalline solid that is soluble in water and has a slight odor. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
N-METHYLBENZAMIDE is used as a key intermediate in the synthesis of various pharmaceuticals. It is used in the production of drugs that target the central nervous system, such as antidepressants and antipsychotics. Its ability to inhibit phosphodiesterase 10A (PDE10A) makes it a promising candidate for the treatment of neurological disorders, such as schizophrenia and Huntington's disease.
Used in Agrochemical Industry:
N-METHYLBENZAMIDE is used as an important pesticide intermediate. It acts as a potent PDE10A inhibitor, which can help in the development of new pesticides with improved efficacy and selectivity. By targeting specific enzymes in pests, N-METHYLBENZAMIDE-based pesticides can provide effective control of various agricultural pests while minimizing harm to non-target organisms and the environment.
Synthesis Reference(s)
Synthetic Communications, 7, p. 549, 1977 DOI: 10.1080/00397917709409275Tetrahedron Letters, 30, p. 451, 1989 DOI: 10.1016/S0040-4039(00)95225-0
Air & Water Reactions
Insoluble in water.
Reactivity Profile
N-METHYLBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard
Flash point data concerning N-METHYLBENZAMIDE are not available, however, N-METHYLBENZAMIDE is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 613-93-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 613-93:
(5*6)+(4*1)+(3*3)+(2*9)+(1*3)=64
64 % 10 = 4
So 613-93-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO/c1-9-8(10)7-5-3-2-4-6-7/h2-6H,1H3,(H,9,10)
