6151-25-3 Usage
Description
Quercetin dihydrate is a bioflavonoid compound with antioxidant, antiviral, antimicrobial, and enzyme inhibitor properties. It is commonly used in various industries for its protective and therapeutic effects.
Uses
Used in Pharmaceutical Industry:
Quercetin dihydrate is used as a capillary protectant for its ability to strengthen blood vessels and reduce their permeability, as well as an antioxidant to neutralize harmful free radicals and protect cells from damage.
Used in Anticancer Applications:
Quercetin dihydrate is used as an antineoplastic agent, exhibiting antiproliferative and pro-apoptotic effects on cancer cells. It also has anti-HIV properties, making it useful in the treatment of viral infections.
Used in Enzyme Inhibition:
Quercetin dihydrate is used as an inhibitor of protein tyrosine kinase, mitochondrial ATPase, and phosphodiesterase. It inhibits PI3-kinase activity and slightly inhibits PIP kinase activity, making it a potential candidate for the development of drugs targeting various diseases.
Used in Food and Beverage Industry:
As a bioflavonoid, antioxidant, antiviral, and antimicrobial agent, Quercetin dihydrate is used in the food and beverage industry to enhance the nutritional value, improve taste, and extend the shelf life of products.
Overall, Quercetin dihydrate is a versatile compound with a wide range of applications in various industries, making it an important substance for research and development.
Biochem/physiol Actions
Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
Purification Methods
Crystallise the flavone from aqueous EtOH and dry at 100o. It also sublimes in a vacuum. IR: 2.5 and 16.7 (KBr). max It complexes with Cu2+, Al3+, Ca2+, Ge4+, Zn2+, Ti4+, Zr4+, Th4+, UO4+ . [Beilstein 18 H 242, 18 I 242, 18 II 236, 18 III/IV 3470, 18/5 V 494.]
Check Digit Verification of cas no
The CAS Registry Mumber 6151-25-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,5 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6151-25:
(6*6)+(5*1)+(4*5)+(3*1)+(2*2)+(1*5)=73
73 % 10 = 3
So 6151-25-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2