617-37-8 Usage
Description
Oxalic acid 1-ethyl ester, also known as ethyl oxalacetate, is an organic compound derived from oxalic acid. It is a colorless liquid with a distinctive odor and is used as a synthetic intermediate in various chemical reactions. Its chemical structure allows for the formation of various compounds with different applications across different industries.
Uses
Used in Pharmaceutical Industry:
Oxalic acid 1-ethyl ester is used as a synthetic intermediate for the production of 2-substituted 3-aryl-4(3H)-quinazolinones, which possess anticonvulsant activities. These compounds are valuable in the development of medications to treat seizures and other related neurological disorders.
Used in Biochemical Research:
In the field of biochemical research, oxalic acid 1-ethyl ester is utilized to prepare nonbenzamidine tetrazole derivatives. These derivatives serve as factor Xa inhibitors, which are essential in the study and treatment of blood clotting disorders and related conditions.
Used in Chemical Synthesis:
Oxalic acid 1-ethyl ester is also employed as a synthetic intermediate in the chemical synthesis of various compounds, contributing to the development of new materials and products in the chemical industry. Its versatility in chemical reactions makes it a valuable component in the synthesis of a wide range of substances with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 617-37-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 617-37:
(5*6)+(4*1)+(3*7)+(2*3)+(1*7)=68
68 % 10 = 8
So 617-37-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H6O4/c1-2-8-4(7)3(5)6/h2H2,1H3,(H,5,6)
617-37-8Relevant articles and documents
Metal-Free Oxidative C=C Bond Cleavage of Electron-Deficient Enamines Promoted by tert -Butyl Hydroperoxide
Adib, Mehdi,Pashazadeh, Rahim,Gohari, Seyed Jamal Adin,Shahsavari, Fatemeh
supporting information, p. 1481 - 1485 (2017/08/15)
A novel tert -butyl hydroperoxide (TBHP)-promoted oxidative C=C double-bond cleavage of enamines is described. Heating a solution of an electron-deficient enamine in chlorobenzene at 80 °C in the presence of TBHP for two hours led to cleavage of the C=C bond. This study offers a new strategy to carry out C=O double-bond formation by the use of TBHP.
Oxidation of β-dicarbonyl compounds with tert-butyl hydroperoxide in the presence of vanadyl acetylacetonate
Stepovik,Gulenova,Kalacheva,Potkina, A. Yu.
experimental part, p. 550 - 558 (2011/06/23)
Oxidation of β-dicarbonyl compounds with tert-butyl hydroperoxide in the presence of vanadyl acetylacetonate (benzene, 20°C) involves the activated methylene group with intermediate formation of trioxo derivatives and is accompanied by decomposition of carbon skeleton. The oxidation products are carbon dioxide, carboxylic acids, and tert-butyl and peroxy esters derived from the latter.
