6196-80-1

Basic information

• Product Name: 1-IODO-4-METHYLPENTANE
• Synonyms: 1-IODO-4-METHYLPENTANE;4-METHYL-1-IODOPENTANE
• CAS NO: 6196-80-1
• Molecular Formula: C₆H₁₃I
• Molecular Weight: 212.07189
• Mol File: 6196-80-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: -68.15°C (estimate)
• Boiling Point: 174.5°C (estimate)
• Appearance: /
• Density: 1.4217
• Refractive Index: 1.4867
• CAS DataBase Reference: 1-IODO-4-METHYLPENTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-4-METHYLPENTANE(6196-80-1)
• EPA Substance Registry System: 1-IODO-4-METHYLPENTANE(6196-80-1)

Safety Data

• Hazardous Substances Data: 6196-80-1(Hazardous Substances Data)

Usage

Type of compound

Alkyl halide, specifically an iodoalkane

Contains

A carbon-iodine bond

Use in organic synthesis

As a reagent for the preparation of various derivatives

Building block

In the synthesis of complex organic molecules

Application

Research and industry

Unique characteristic

Different reactivity due to the presence of the iodine atom compared to non-iodinated counterparts

Value

Versatile chemical compound in organic chemistry and chemical research

Upstream product

• 626-89-1 4-Methyl-1-pentanol 
• 646-07-1 4-Methylpentanoic acid 
• 10034-85-2 hydrogen iodide 
• 626-88-0 1-bromo-5-methylpentane 

Downstream Products

• 20718-61-0 4-isohexyloxy-benzaldehyde 
• 55830-20-1 2-methyloctadecan-8-one 
• 54910-51-9 (2S-cis)-7,8-epoxy-2-methyloctadecane 
• 120040-57-5 2-methyl-5-(phenylsulfonyl)pentan-2-ol 
• 122715-65-5 2,2,6-Trimethylheptanoic acid 
• 81291-39-6 2,2,6-Trimethyl-heptanoic acid methyl ester 
• 86534-87-4 (2R,6R)-2,6,10-Trimethyl-undecanoic acid (1R,2R,3S,4S)-3-[benzenesulfonyl-(3,5-dimethyl-phenyl)-amino]-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 116561-87-6 (7R,8R)-8-((S)-Benzenesulfinyl)-2-methyl-octadecan-7-ol 
• 116561-86-5 (S)-1-((S)-Benzenesulfinyl)-7-methyl-octan-2-ol 
• 116561-85-4 (R)-1-((S)-Benzenesulfinyl)-7-methyl-octan-2-ol 
• 60148-94-9 (R)-2,6-dimethyl-heptanoic acid 

Relevant articles and documents

Electrophilic Iron Catalyst Paired with a Lithium Cation Enables Selective Functionalization of Non-Activated Aliphatic C?H Bonds via Metallocarbene Intermediates

Combining an electrophilic iron complex [Fe(Fpda)(THF)]2 (3) [Fpda=N,N′-bis(pentafluorophenyl)-o-phenylenediamide] with the pre-activation of α-alkyl-substituted α-diazoesters reagents by LiAl(ORF)4 [ORF=(OC(CF3)3] provides unprecedented access to selective iron-catalyzed intramolecular functionalization of strong alkyl C(sp3)?H bonds. Reactions occur at 25 °C via α-alkyl-metallocarbene intermediates, and with activity/selectivity levels similar to those of rhodium carboxylate catalysts. Mechanistic investigations reveal a crucial role of the lithium cation in the rate-determining formation of the electrophilic iron-carbene intermediate, which then proceeds by concerted insertion into the C?H bond.

Improved syntheses of high hole mobility phthalocyanines: A case of steric assistance in the cyclo-oligomerisation of phthalonitriles

It has been shown that the base-initiated cyclo-oligomerisation of phthalonitriles is favoured by bulky α-substituents making it possible to obtain the metal-free phthalocyanine directly and in high yield. The phthalocyanine with eight α-isoheptyl substituents gives a high time-of-flight hole mobility of 0.14 cm2·V -1·s-1 within the temperature range of the columnar hexagonal phase, that is 169-189 °C.

Enantioselective synthesis of α-methyl carboxylic acids using a DiTOX chiral auxiliary

Five α-methyl carboxylic acids have been prepared with high e.e.s using 1,3-dithiane 1-oxide (DiTOX) units as the stereocontrolling elements and sources of chirality.