6197-30-4 Usage
Description
Octocrylene, a diarylmethane, is a yellow viscous liquid that is insoluble in water. It is an ester formed by the condensation of a diphenylcyanoacrylate with 2-ethylhexanol and is commonly used in sunscreens and cosmetics. Octocrylene is an effective oil-soluble liquid UV-B filter with excellent dissolving properties for crystalline UV filters.
Uses
Used in Sunscreen Industry:
Octocrylene is used as a UVB sunscreen for its ability to absorb UV rays, protecting the skin from sun damage. It is chemically related to cinnamates and is employed to boost SPF and improve water resistance in a given formulation. Octocrylene is photostable and can enhance the photostability of other sunscreens.
Octocrylene is used as an effective SPF booster and waterproofing enhancer for its strong water-resistant properties and broad-band absorption range. It is being evaluated by many companies for its potential in the sunscreen industry. However, its cost and approved usage level of 7 to 10 percent in both the United States and the European Union can limit its use. Additionally, some studies indicate that it may cause allergic reactions in skin with a history of photoallergy.
benefits
Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene protects the skin from the harmful effects of the sun and premature skin aging. It helps prevent the risk of skin cancer. This filter mainly absorbs UVB rays, and shorter UVA rays, which are responsible for aging but also for skin cancer.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Octocrilene is an ester derivative. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Fire Hazard
Flash point data for Octocrilene are not available. Octocrilene is probably combustible.
Flammability and Explosibility
Nonflammable
Contact allergens
Octocrylene is an anti-UVB filter used in cosmetics
that may induce photoallergic contact dermatitis.
Side effects
Some people are concerned about the body’s ability to absorb octocrylene, which can present in the blood, urine, and breast milk. It may promote the production of free radicals, which can damage DNA, potentially increasing the risk of melanoma. However, further research is necessary.People with sensitive skin or skin conditions, such as eczema, may prefer to avoid products containing octocrylene. Alternatively, a person can perform a patch test before using a product containing octocrylene for the first time. The patch test should indicate if an individual is allergic or sensitive to an ingredient in the product.The Food and Drug Administration (FDA) evaluated the safety of octocrylene for use in sunscreen products and found that concentrations of up to 10% are safe.The European Scientific Committee on Consumer Safety (SCCS) also stated that octocrylene is safe in products containing concentrations of no more than 10%.Berardesca, E.,et al.(2019). Review of the safety of octocrylene used as an ultraviolet filter in cosmetics.https://onlinelibrary.wiley.com/doi/full/10.1111/jdv.15945
Safety Profile
Low toxicity by ingestion. Whenheated to decomposition it emits toxic vapors of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 6197-30-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,9 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6197-30:
(6*6)+(5*1)+(4*9)+(3*7)+(2*3)+(1*0)=104
104 % 10 = 4
So 6197-30-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3
6197-30-4Relevant articles and documents
Preparation method of cyanoacrylate ultraviolet light absorber
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Paragraph 0109-0110, (2020/04/29)
The invention provides a preparation method of a cyanoacrylate ultraviolet light absorber. Benzophenone compounds represented by general formula I with cyanoacetate under a weakly alkaline condition by using activated carbon grafted acidic ionic liquid as a catalyst to generate a compound represented by general formula II. The preparation method of the cyanoacrylate ultraviolet light absorber adopts the activated carbon grafted acidic ionic liquid catalyst to replace acetic acid, so that the preparation method has the advantages of easiness in recycling of the catalyst, high product yield, fewthree wastes, and convenience in post-treatment, and is an economical, practical and environment-friendly technology.
A NOVEL PROCESS FOR THE PREPARATION OF 2-CYANO- 3,3- DIARYLACRYLATES
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Page/Page column 9; 10, (2014/11/13)
The present invention relates to a novel process for preparation of 2-Cyano-3,3- diarylacrylates of Formula I by the Knoevenagel condensation of Cyanoacetic esters and Arylketones using ammonium compound and acetic acid and without the use of organic solvent.
A composition for lightening skin and hair
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, (2014/10/28)
Suggested is a composition comprising (a) sclareolide and (b1) at least one tyrosinase inhibitor; and/or (b2) at least one sun protection factor; and/or (b3) at least one anti-oxidants; and/or (b4) at least one anti-inflammatory agent; and/or (b5) at least one desquamating agent.