62005-48-5Relevant articles and documents
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit
Spadoni, Gilberto,Bedini, Annalida,Furiassi, Lucia,Mari, Michele,Mor, Marco,Scalvini, Laura,Lodola, Alessio,Ghidini, Andrea,Lucini, Valeria,Dugnani, Silvana,Scaglione, Francesco,Piomelli, Daniele,Jung, Kwang-Mook,Supuran, Claudiu T.,Lucarini, Laura,Durante, Mariaconcetta,Sgambellone, Silvia,Masini, Emanuela,Rivara, Silvia
, p. 7902 - 7916 (2018/09/18)
Activation of melatonin receptors and inhibition of fatty acid amide hydrolase (FAAH) have both shown potential benefits for the treatment of glaucoma. To exploit the combination of these biological activities in single therapeutic agents, we designed dua
PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES
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Page/Page column 5, (2012/09/10)
The invention relates to a process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides and to the useful intermediate compounds of such process. The process allows to obtain the desired products in high yields and purity. Th
Direct, one-pot reductive alkylation of anilines with functionalized acetals mediated by triethylsilane and tfa. straightforward route for unsymmetrically substituted ethylenediamine
Righi, Marika,Bedini, Annalida,Piersanti, Giovanni,Romagnoli, Federica,Spadoni, Gilberto
supporting information; experimental part, p. 704 - 707 (2011/03/22)
A new, robust, and reliable method has been developed for the selective reductive N-alkylation of primary and secondary aromatic amines with some functionalized acetals using TFA/Et3SiH as a reagent combination. A variety of unsymmetrically sub