620151-84-0

Basic information

• Product Name: (S)-ethyl 4,4-dimethyl-N-(3-phenylpropionyl)pyroglutamate
• Synonyms: (S)-ethyl 4,4-dimethyl-N-(3-phenylpropionyl)pyroglutamate
• CAS NO: 620151-84-0
• Molecular Weight: 317.385
• Mol File: 620151-84-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 4,4-dimethyl-N-(3-phenylpropionyl)pyroglutamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 4,4-dimethyl-N-(3-phenylpropionyl)pyroglutamate(620151-84-0)
• EPA Substance Registry System: (S)-ethyl 4,4-dimethyl-N-(3-phenylpropionyl)pyroglutamate(620151-84-0)

Safety Data

• Hazardous Substances Data: 620151-84-0(Hazardous Substances Data)

Upstream product

• 645-45-4 hydrocinnamic acid chloride 
• 221637-35-0 (S)-ethyl 4,4-dimethyl-5-oxopyrrolidine-2-carboxylate 

Downstream Products

• 104-53-0 3-phenyl-propionaldehyde 
• 620152-51-4 (2S)-ethyl N-(1-hydroxy-3-phenylpropyl)-4,4-dimethylpyroglutamate 
• 2021-28-5 ethyl dihydrocinnamate 
• 1083-30-3 dihydrochalcone 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 17077-46-2 4-(3-phenyl-propionyl)-morpholine 

Relevant articles and documents

Chemoselective Nucleophilic Attack on N-Acyl Derivatives of (S)-Ethyl 4,4-Dimethyl Pyroglutamate (DMPG)

(Matrix presented) Heteronucleophiles and C-nucleophiles chemoselectively react with N-acyl (S)-ethyl 4,4-dimethyl pyroglutamate (DMPG) affording esters, amides, and ketones in high yield. The intramolecular process allows the stereoselective formation of β-hydroxy acids likely by formation and ring opening of the corresponding β-lactones.