622-39-9 Usage
Description
2-N-PROPYLPYRIDINE, also known as 2-(N-propyl)pyridine, is an organic compound with the molecular formula C8H11N. It is a colorless to pale yellow liquid with a strong, characteristic odor. 2-N-PROPYLPYRIDINE is derived from pyridine, a heterocyclic aromatic compound, by substituting one hydrogen atom with a propyl group. Its unique chemical structure and properties make it a versatile compound with various applications across different industries.
Uses
Used in Flavor and Fragrance Industry:
2-N-PROPYLPYRIDINE is used as a flavoring agent for its characteristic aroma. It is particularly favored in the creation of artificial flavors for the food and beverage industry due to its ability to impart a unique taste and smell to products. 2-N-PROPYLPYRIDINE's aroma threshold values, detectable at 0.011 mg/m3 in air, make it an effective ingredient in the formulation of various fragrances and perfumes.
Used in Pharmaceutical Industry:
2-N-PROPYLPYRIDINE serves as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a building block for the development of new drugs, particularly those targeting the central nervous system. 2-N-PROPYLPYRIDINE's versatility in chemical reactions makes it a valuable asset in the design and synthesis of novel therapeutic agents.
Used in Chemical Research:
As a versatile organic compound, 2-N-PROPYLPYRIDINE is used in various chemical research applications. It is employed as a reagent or a starting material in the synthesis of complex organic molecules, including those with potential applications in materials science, agrochemicals, and other specialty chemicals.
Used in the Production of Agrochemicals:
2-N-PROPYLPYRIDINE is utilized as a key component in the development of agrochemicals, such as pesticides and herbicides. Its unique chemical properties enable it to be incorporated into the molecular structure of these chemicals, enhancing their effectiveness in controlling pests and weeds in agricultural settings.
Check Digit Verification of cas no
The CAS Registry Mumber 622-39-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 622-39:
(5*6)+(4*2)+(3*2)+(2*3)+(1*9)=59
59 % 10 = 9
So 622-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N/c1-2-5-8-6-3-4-7-9-8/h3-4,6-7H,2,5H2,1H3
622-39-9Relevant articles and documents
Photocatalytic Hydromethylation and Hydroalkylation of Olefins Enabled by Titanium Dioxide Mediated Decarboxylation
Zhu, Qilei,Nocera, Daniel G.
supporting information, p. 17913 - 17918 (2020/12/04)
A versatile method for the hydromethylation and hydroalkylation of alkenes at room temperature is achieved by using the photooxidative redox capacity of the valence band of anatase titanium dioxide (TiO2). Mechanistic studies support a radical-based mechanism involving the photoexcitation of TiO2 with 390 nm light in the presence of acetic acid and other carboxylic acids to generate methyl and alkyl radicals, respectively, without the need for stoichiometric base. This protocol is accepting of a broad scope of alkene and carboxylic acids, including challenging ones that produce highly reactive primary alkyl radicals and those containing functional groups that are susceptible to nucleophilic substitution such as alkyl halides. This methodology highlights the utility of using heterogeneous semiconductor photocatalysts such as TiO2 for promoting challenging organic syntheses that rely on highly reactive intermediates.
Palladium acetate-catalyzed one-pot synthesis of mono- And disubstitued pyridines
Mikami, Shunya,Toyota, Masahiro
, p. 1315 - 1321 (2019/08/01)
A Pd-catalyzed one-pot synthesis of mono- and disubstituted pyridines was developed. The substituted pyridines were obtained from ketones or an aldehyde and 1,3-diaminopropane using a combination of catalytic Pd(OAc)2 and Cu(OAc)2. High-concentration reaction conditions enabled this catalytic reaction to be acid-free.
Nickel-Catalyzed Hydrogenolysis and Conjugate Addition of 2-(Hydroxymethyl)pyridines via Organozinc Intermediates
Hanna, Luke E.,Harris, Michael R.,Domon, Kenji,Jarvo, Elizabeth R.
supporting information, p. 6304 - 6307 (2017/12/08)
2-Hydroxymethylpyridines undergo nickel-catalyzed hydrogenolysis upon activation with a chlorophosphate. Reactions employ diethylzinc and are proposed to proceed through secondary benzylzinc reagents. Quenching with deuteromethanol provides straightforward incorporation of a deuterium label in the benzylic position. Intramolecular conjugate additions with α,β-unsaturated esters are also demonstrated and support the intermediacy of a benzylzinc complex.
