62288-83-9 Usage
Description
Desmopressin, also known as DDAVP, is a synthetic analog of the hormone vasopressin. It is a white to off-white crystalline solid that possesses antidiuretic and hemostatic properties. Desmopressin works by increasing the reabsorption of water in the kidneys, reducing urine output, and promoting the release of von Willebrand factor, factor VIII, and tissue plasminogen activator, which improves hemostasis.
Uses
Used in Pharmaceutical Industry:
Desmopressin is used as an antidiuretic for the treatment of conditions characterized by excessive urination or nocturia, such as diabetes insipidus and primary nocturnal enuresis. It helps to reduce urine output by promoting water reabsorption in the kidneys.
Used in Hematology:
Desmopressin is used as a hemostatic agent for the management of bleeding disorders, such as von Willebrand disease and hemophilia A. It enhances hemostasis by increasing plasma levels of von Willebrand factor, factor VIII, and tissue plasminogen activator, which aids in blood clot formation and reduces bleeding episodes.
Used in Nephrology:
Desmopressin is used as a diagnostic tool in the evaluation of suspected diabetes insipidus. It is administered to patients to assess their response to the antidiuretic hormone, which can help in determining the underlying cause of the condition.
Used in Obstetrics and Gynecology:
Desmopressin is used to reduce blood loss during and after certain surgical procedures, such as cesarean section and uterine fibroid removal. Its hemostatic properties help to minimize bleeding and the need for blood transfusions.
Used in Pediatrics:
Desmopressin is used to manage bedwetting (nocturnal enuresis) in children. Its antidiuretic effect reduces the production of urine during sleep, helping to prevent bedwetting episodes.
Used in Cardiology:
Desmopressin is used to improve hemostasis in patients with certain cardiovascular conditions, such as acute coronary syndrome or during cardiac catheterization. It helps to stabilize blood clots and prevent excessive bleeding.
Check Digit Verification of cas no
The CAS Registry Mumber 62288-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,2,8 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 62288-83:
(7*6)+(6*2)+(5*2)+(4*8)+(3*8)+(2*8)+(1*3)=139
139 % 10 = 9
So 62288-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C46H64N14O12S2.C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);1H3,(H,3,4)/t28-,29-,30-,31-,32-,33-,34-;/m0./s1
62288-83-9Relevant articles and documents
IMPROVED PROCESS FOR THE PREPARATION OF DESMOPRESSIN OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS
-
, (2012/04/23)
The present invention relates to a novel and improved process for the preparation of 1-deamino-8-D-arginine vasopressin (Desmopressin) or its pharmaceutically acceptable salts thereof and also relates to an improved process for the purification of Desmopressin or its pharmaceutically acceptable salts. Further, the present invention also relates to pharmaceutical composition of Desmopressin or its pharmaceutically acceptable salts thereof.
