6237-61-2

Basic information

• Product Name: 2-Butenedioic acid, 2-benzoyl-, dimethyl ester, (2E)-
• CAS NO: 6237-61-2
• Molecular Formula: C13H12O5
• Molecular Weight: 248.235
• Mol File: 6237-61-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Butenedioic acid, 2-benzoyl-, dimethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenedioic acid, 2-benzoyl-, dimethyl ester, (2E)-(6237-61-2)
• EPA Substance Registry System: 2-Butenedioic acid, 2-benzoyl-, dimethyl ester, (2E)-(6237-61-2)

Safety Data

• Hazardous Substances Data: 6237-61-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 352-93-2 diethyl sulphide 
• 107-47-1 sulfure de di tert-butyle 
• 100-68-5 methyl-phenyl-thioether 
• 139-66-2 diphenyl sulfide 
• 115852-14-7 methyl 2-methoxy-5-phenyl-furan-4-carboxylate 
• 143813-02-9 5-Phenyl-3H-[1,2]dioxole-3,4-dicarboxylic acid dimethyl ester 
• 115852-17-0 2-Hydroperoxy-5,5-dimethoxy-2-phenyl-2,5-dihydro-furan-3-carboxylic acid methyl ester 

Downstream Products

• 1333158-60-3 dimethyl 2-phenyl-5-(trifluoromethyl)furan-3,4-dicarboxylate 
• 6237-64-5 2-Benzoyl-bicyclo<2.2.1>heptan-trans-2,3-dicarbonsaeure-dimethylester 
• 121643-54-7 dimethyl 2-benzoyloxirane-2,3-dicarboxylate 
• 121643-54-7 dimethyl 2-benzoyloxirane-2,3-dicarboxylate 

Relevant articles and documents

Novel pyridine-catalyzed reaction of dimethyl acetylenedicarboxylate with aldehydes and N-tosylimines: Efficient synthesis of 2-benzoylfumarates and 1-azadienes

A novel reaction of 1,4-dipolar intermediate 3, generated from pyridine and dimethyl acetylenedicarboxylate, with aromatic aldehydes, resulted in the facile synthesis of 2-benzoylfumarates via the elimination of pyridine, whereas with N-tosylimines as dipolarophiles the reaction afforded highly substituted 1-azadienes. The reaction of pyridine and dimethyl acetylenedicarboxylate with N-substituted isatins, resulted in a novel three component condensation, affording spiropyrido[2,1-b][1,3]oxazino derivatives in high yields via 1,4-dipolar cycloaddition.

Nicotinic acid functionalized organomodified silica as an efficient heterogeneous catalyst for the synthesis of benzoyl fumarate

A new hybrid catalyst has been developed by incorporating nicotinic acid onto an organomodified silica. The catalyst was applied as a heterogeneous catalyst for the synthesis of benzoyl fumarate. The reactions work well in the presence of 20 wt % of the catalyst at room temperature to produce the desired products in high yield. The catalyst could be recovered and reused without appreciable change in activity.

Reactions of Arylaldehydes and N-Sulfonated Imines with Dimethyl Acetylenedicarboxylate Catalyzed by Nitrogen and Phosphine Lewis Bases

(Equation presented) In the reaction of arylaldehydes or N-sulfonated imines (0.5 mmol) with dimethyl acetylenedicarboxylate (DMAD) (0.6 mmol) catalyzed by pyridine or DMAP (20 mol %), we found that (E)-2-aryl-but-2- enedioic acid dimethyl ester 1 or (E)-2-[aryl-(toluene-4-sulfonylimino)methyl]- but-2-enedioic acid dimethyl ester 2 was formed in good yields at 60°C in THF. A plausible mechanism has been proposed.