624-73-7 Usage
Description
1,2-Diiodoethane, also known as ethylene diiodide, is an organic compound with the chemical formula C2H4I2. It is a dark brown crystalline solid that is highly reactive due to the presence of two iodine atoms. This reactivity makes it a versatile compound in various chemical reactions and applications.
Uses
1. Used in Chemical Synthesis:
1,2-Diiodoethane is used as a C-X bond formation reagent, which is crucial in the synthesis of various organic compounds. Its ability to form carbon-halogen bonds makes it a valuable intermediate in the production of different chemical products.
2. Used in Pharmaceutical Industry:
1,2-Diiodoethane serves as a pharmaceutical intermediate, playing a significant role in the development and synthesis of various drugs. Its unique properties allow it to be used in the creation of new medications and therapeutic agents.
3. Used in Synthesis of SmI2-H2O Complex:
1,2-Diiodoethane can be used to synthesize samarium(II) iodide-water complex (SmI2-H2O complex), a single-electron transfer reagent. This complex is essential in the further synthesis of 3-hydroxy carboxylic acids, which are vital components in the pharmaceutical and chemical industries.
4. Used in Synthesis of Regioselective Homopropargyl Alcohols:
1,2-Diiodoethane is employed in the synthesis of derivatives of regioselective homopropargyl alcohols using sonochemical Barbier-type reaction conditions. This application highlights its versatility in organic synthesis and its ability to produce specific compounds with desired properties.
5. Used as an Iodine Source and Reagent for Dehydroxy-iodination of Alcohols:
As an iodine source, 1,2-diiodoethane is an effective reagent for the dehydroxy-iodination of alcohols. This reaction is essential in the synthesis of various organic compounds, particularly those requiring the introduction of iodine atoms or the removal of hydroxyl groups.
Purification Methods
Dissolve it in ether, wash it with saturated aqueous Na2S2O3, dry over MgSO4 and evaporate the ether in vacuo and distil it. Store it in the dark. [Molander et al. J Am Chem Soc 109 453 1987]. [Beilstein 1 IV 169.]
Check Digit Verification of cas no
The CAS Registry Mumber 624-73-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 624-73:
(5*6)+(4*2)+(3*4)+(2*7)+(1*3)=67
67 % 10 = 7
So 624-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C2H4I2/c3-1-2-4/h1-2H2
624-73-7Relevant articles and documents
Carbodeoxygenation of biomass: The carbonylation of glycerol and higher polyols to monocarboxylic acids
Coskun, Timur,Conifer, Christopher M.,Stevenson, Laura C.,Britovsek, George J. P.
supporting information, p. 6840 - 6844 (2013/07/05)
Glycerol is converted to a mixture of butyric and isobutyric acid by rhodium- or iridium-catalysed carbonylation using HI as the co-catalyst. The initial reaction of glycerol with HI results in several intermediates that lead to isopropyl iodide, which upon carbonylation forms butyric and isobutyric acid. At low HI concentration, the intermediate allyl iodide undergoes carbonylation to give vinyl acetic acid and crotonic acid. Higher polyols CnH n+2(OH)n are carbonylated to the corresponding C n+1 mono-carboxylic acids. Copyright
Reactions of trimethyliodosilane with mono-, di-, and trioxacycloalkanes
Voronkov, M. G.,Dubinskaya, E. I.
, p. 13 - 32 (2007/10/02)
The reactions of Me3SiI with mono-, di-, and trioxacycloalkanes have been studied first.Preparative methods for the synthesis of some promising synthones, namely α,ω-diiodoalkanes, α,ω-alkanediols, and iodomethyl ω-iodoalkyl ethers, have been developed based on these reactions.The effect of the cycle size and the nature of the substituent on the course of the reactions is demonstrated.Schemes for the mechanism of the reactions are suggested.
Halogenobis(N,N-dialkyldithiocarbamato)iron(III) Complexes as Potential Catalysts for Halogen Addition Reactions to Alkenes
Tsipis, Constantinos A.,Katsoulos, George A.,Vakoulis, Fotios D.
, p. 1404 - 1405 (2007/10/02)
In the presence of a catalytic amount of iron(III) halogenobisdithiocarbamates, the addition of molecular halogens to alkenes occurs rapidly to afford cis-addition products.
