6242-16-6

Basic information

• Product Name: 21-acetoxy-11α,17-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
• Synonyms: 21-acetoxy-11α,17-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
• CAS NO: 6242-16-6
• Molecular Weight: 416.514
• Mol File: 6242-16-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 21-acetoxy-11α,17-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 21-acetoxy-11α,17-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione(6242-16-6)
• EPA Substance Registry System: 21-acetoxy-11α,17-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione(6242-16-6)

Safety Data

• Hazardous Substances Data: 6242-16-6(Hazardous Substances Data)

Downstream Products

• 912-38-9 21-acetoxy-9,11β-epoxy-17-hydroxy-16α-methyl-9β-pregna-1,4-diene-3,20-dione 
• 10106-41-9 17α,21-dihydroxy-16α-methyl-1,4,9(11)-pregnatriene-3,20-dione 21-acetate 
• 1177-87-3 betamethasone 

Relevant articles and documents

Synthesis method of beclomethasone dipropionate intermediate 11 - β hydroxypregnane

The invention belongs to the field of a medicine preparation, and particularly relates to a synthesis method of an alclometasone dipropionate intermediate of 11-beta hydroxypregna. The 11-beta hydroxypregna is obtained by using a compound shown as a formula II as raw materials and performing free radical reaction under the effects of zinc powder, hexahydrate chromium trichloride and thioglycolic acid. The method provided by the invention has the advantages that the operation is simple; the yield is high; the method is suitable for industrial production.