625-37-6 Usage
Description
Crotonamide, also known as but-2-enamide, is a chemical compound with the molecular formula C4H7NO. It is an amide derivative of crotonic acid, characterized by its colorless to pale yellow liquid appearance and a pungent odor. Being insoluble in water but soluble in organic solvents, Crotonamide is recognized as a potentially hazardous substance that requires careful handling and storage. Its versatile chemical properties make it a valuable starting material in the synthesis of a range of pharmaceuticals and organic compounds, with potential applications across medicine, agriculture, and industry.
Uses
Used in Pharmaceutical Synthesis:
Crotonamide is used as a starting material for the synthesis of various pharmaceuticals due to its reactive amide group and its ability to participate in a wide range of chemical reactions. This makes it a key component in the development of new drugs and medicinal compounds.
Used in Organic Chemistry:
In the field of organic chemistry, Crotonamide is utilized as an intermediate in the synthesis of organic compounds. Its unique structure allows it to be a building block for more complex molecules, contributing to the advancement of organic synthesis techniques.
Used in Agricultural Applications:
Crotonamide may also find use in agriculture, potentially serving as a component in the development of agrochemicals or as a tool in the study of plant and crop responses to various stimuli.
Used in Industrial Processes:
Its potential applications in industry could include use as a precursor in the production of specialty chemicals, materials, or as a component in the formulation of various industrial products.
Given the provided materials, the specific uses of Crotonamide in medicine, agriculture, and industry are not detailed, but the compound's role as a starting material in the synthesis of various compounds suggests a broad range of potential applications across these fields. Further research and development would be necessary to fully explore and realize these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 625-37-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 625-37:
(5*6)+(4*2)+(3*5)+(2*3)+(1*7)=66
66 % 10 = 6
So 625-37-6 is a valid CAS Registry Number.
625-37-6Relevant articles and documents
A Brevibacterium process for synthesizing amide
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Paragraph 0097; 0098; 0099; 0100, (2017/04/29)
The invention discloses a method for synthesizing amide through nitrile hydrolysis. The method comprises the following steps: adding nitrile, acetaldoxime, water, a water-soluble rhodium complex to a reaction vessel, and cooling to room temperature after reaction of a reaction mixture for several hours at the temperature of 50-80 DEG C; and adding ethyl acetate for extraction so as to obtain an organic layer, and carrying out rotary evaporation to remove a solvent, thus obtaining a target product. Compared with a method for synthesizing amide through nitrile hydrolysis by using oxime as a water source in a transition metal catalysis process, the method has the advantages that a used catalyst is low in loading and does not contain a phosphine ligand seriously polluting environments, synthesis can be performed in air, and nitrogen protection is not needed; and therefore, the method meets the green chemistry requirements and has a wide development prospect.
Superacidic activation of α,β-unsaturated amides and their electrophilic reactions
Koltunov, Konstantin Yu.,Walspurger, Stephane,Sommer, Jean
, p. 4039 - 4047 (2007/10/03)
The electrophilic reactivity of α,β-unsaturated amides towards weak nucleophiles such as arenes and cyclohexane, initiated either with triflic acid (CF3SO3H) or with excess AlCl3, has been studied. The amides generally condense readily with aromatics in the presence of AlCl3 to give 3-arylpropionamides and related compounds in excellent yields, while some amides also undergo selective ionic hydrogenation with cyclohexane to give saturated amides. The proposed mechanism of these reactions involves dicationic intermediates (superelectrophiles). The direct observation of a dicationic species (by low-temperature NMR) is reported. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
TREATMENT OF PLATELET DERIVED GROWTH FACTOR RELATED DISORDERS SUCH AS CANCERS
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, (2008/06/13)
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