627511-79-9

Basic information

• Product Name: Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-8-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester
• Synonyms: Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-8-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester
• CAS NO: 627511-79-9
• Molecular Weight: 665.028
• Mol File: 627511-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-8-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-8-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester(627511-79-9)
• EPA Substance Registry System: Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-8-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester(627511-79-9)

Safety Data

• Hazardous Substances Data: 627511-79-9(Hazardous Substances Data)

Upstream product

• 627511-83-5 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester 
• 627511-95-9 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester 
• 627511-97-1 2,2-Dimethyl-propionic acid 2-{(2S,4S,6R,8S,10S)-8-[2-(4-methoxy-benzyloxy)-ethyl]-4-methyl-4,10-bis-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-ethyl ester 
• 627511-98-2 2-{(2S,4S,6R,8S,10S)-8-[2-(4-Methoxy-benzyloxy)-ethyl]-4-methyl-4,10-bis-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-ethanol 
• 627511-85-7 {(2R,4S,6R,8S,10S)-8-[2-(4-Methoxy-benzyloxy)-ethyl]-4-methyl-4,10-bis-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-acetaldehyde 
• 627511-84-6 2,2-Dimethyl-propionic acid 2-[(2S,4S,6R,8S,10S)-4,10-dihydroxy-8-(2-hydroxy-ethyl)-4-methyl-1,7-dioxa-spiro[5.5]undec-2-yl]-ethyl ester 
• 209340-30-7 (S)-2-((S)-2-Benzyloxy-4-trityloxy-butyl)-oxirane 
• 400-53-3 trimethylsilyl trifluoroacetate 
• 627511-99-3 Acetic acid (2S,4S,6R,8R,10S)-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-8-(2-oxo-butyl)-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-4-yl ester 

Downstream Products

• 627512-00-9 (2S,3R,4S,5S,6S)-1-{(2S,4S,6R,8S,10S)-10-Hydroxy-8-[2-(4-methoxy-benzyloxy)-ethyl]-4-methyl-4-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-6-(4-methoxy-benzyloxy)-3,5-dimethyl-octane-2,4-diol 
• 627511-89-1 3,3,3-trifluoro-2-methoxy-2-phenyl-propionic acid 1-(3-{10-acetoxy-8-[2-(4-methoxy-benzyloxy)-ethyl]-4-methyl-4-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-1-methyl-2-oxo-propyl)-3-(4-methoxy-benzyloxy)-2-methyl-pentyl ester 
• 627511-87-9 Acetic acid (2S,4S,6R,8R,10S)-8-[(3S,4R,5S,6S)-4-hydroxy-6-(4-methoxy-benzyloxy)-3,5-dimethyl-2-oxo-octyl]-2-[2-(4-methoxy-benzyloxy)-ethyl]-10-methyl-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-4-yl ester 

Relevant articles and documents

Formal total synthesis of altohyrtin C (spongistatin 2). Part 1: Aldol approach to unite AB and CD spiroacetals

The Mukaiyama aldol coupling of the second-generation C1-C14 (AB) fragment of altohyrtins (spongistatins) with the model α-methyl-β -alkoxyaldehydes revealed that the stereochemistry at the newly formed carbon centers was controlled by the β-alkoxy chiral center of the model aldehydes. The union of the AB fragment with the C15-C28 (CD) fragment under the same conditions gave the fully elaborated C1-C28 (ABCD) subunit in good yield.