630126-05-5

Basic information

• Product Name: 1H-Imidazole, 2-methyl-1-[4-nitro-2-(trifluoromethyl)phenyl]-
• CAS NO: 630126-05-5
• Molecular Formula: C11H8F3N3O2
• Molecular Weight: 271.199
• Mol File: 630126-05-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-methyl-1-[4-nitro-2-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-methyl-1-[4-nitro-2-(trifluoromethyl)phenyl]-(630126-05-5)
• EPA Substance Registry System: 1H-Imidazole, 2-methyl-1-[4-nitro-2-(trifluoromethyl)phenyl]-(630126-05-5)

Safety Data

• Hazardous Substances Data: 630126-05-5(Hazardous Substances Data)

Upstream product

• 693-98-1 2-methylimidazole 
• 400-74-8 2-Fluoro-5-nitrobenzotrifluoride 
• 288-32-4 1H-imidazole 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

WNT PATHWAY MODULATORS

The invention provides a compound of structure Ar1-Ar2-X-C(R1R2)-C(=O)-N(R3)-Ar3-Ar4 for modulating WNT activity. In this structure, Ar1, Ar2, Ar3 and Ar4 are, independently, optionally substituted aryl or heteroaryl groups; R1 and R3 are, independently, H or optionally substituted alkyl groups; R2 is H or an optionally substituted alkyl group or an alkylene group which, together with the carbon atom to which it is attached and X, forms a non-aromatic ring or an alkylene group which, together with the carbon atom to which it is attached and X and two adjacent atoms of Ar2, forms a non-aromatic ring; X is O, CR4R5, N or NR4, wherein if X is N, it is bonded to R2; R4 is H, optionally substituted alkyl or an alkylene chain, optionally containing a heteroatom and/or a carbonyl group, which, together with the C or N to which it is attached and two adjacent atoms of Ar2, forms a non-aromatic ring; R5 is H, NH2 or an optionally substituted alkyl group.