63018-69-9 Usage
Description
Benz[a]anthracene-7-acetonitrile is a benzanthracene derivative, which is a type of polycyclic aromatic compound. It is characterized by its unique molecular structure that features a benzene ring fused to an anthracene core, with a nitrile functional group attached at the 7th position. Benz[a]anthracene-7-acetonitrile serves as an important intermediate in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
Benz[a]anthracene-7-acetonitrile is used as an intermediate in the synthesis of growth-inhibitory polycyclic compounds. These compounds have potential applications in the development of pharmaceuticals targeting the inhibition of cell growth in cancerous cells, making it a valuable component in the discovery and production of novel anticancer drugs.
Used in Chemical Research:
As a benzanthracene derivative, Benz[a]anthracene-7-acetonitrile is also utilized in chemical research for the investigation of the properties and reactions of polycyclic aromatic compounds. This can lead to the development of new synthetic methods, the discovery of new chemical reactions, and the creation of new compounds with potential applications in various fields.
Safety Profile
Questionable carcinogen withexperimental tumorigenic data. When heated to decomposition it emits toxic fumes ofNOx and CN - .
Check Digit Verification of cas no
The CAS Registry Mumber 63018-69-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,0,1 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63018-69:
(7*6)+(6*3)+(5*0)+(4*1)+(3*8)+(2*6)+(1*9)=109
109 % 10 = 9
So 63018-69-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H13N/c21-12-11-19-17-8-4-2-6-15(17)13-20-16-7-3-1-5-14(16)9-10-18(19)20/h1-10,13H,11H2
63018-69-9Relevant articles and documents
Synthesis of a Series of Novel Polycyclic Aromatic Systems: Isomers of Benzanthracene Containing a Cyclopenta-Fused Ring
Sangaiah, R.,Gold, A.,Toney, G. E.
, p. 1632 - 1638 (2007/10/02)
The four possible isomers of benzanthracene containing a cyclopenta-fused ring have been synthesized and characterized.These systems are of interest for structure-activity studies in bioactivation because of their predicted high level of activity.Formation of fused five-membered rings by intramolecular cyclodehydration, often difficult to accomplish, was found to be smoothly effected in anhydrous HF, provided the reactivity index (Nt) for the appropriate electrophilic addition was favorable.The dihydro polycyclic aromatic alcohols obtained from reduction of the c orresponding keto cyclodehydration products were best dehydrated to the desired PAH by activity grade I neutral alumina in refluxing benzene.This dehydration proceeds in high yield without the formation of isomeric or polymeric side products that occurred even under such mild acid catalysis as p-toluenesulfonic acid.