6333-33-1

Basic information

• Product Name: 2,4-dichloro-6-(chloromethyl)phenol
• Synonyms: phenol, 2,4-dichloro-6-(chloromethyl)-
• CAS NO: 6333-33-1
• Molecular Formula: C₇H₅Cl₃O
• Molecular Weight: 211.473
• Mol File: 6333-33-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 284.3°C at 760 mmHg
• Flash Point: 125.8°C
• Density: 1.516g/cm³
• Vapor Pressure: 0.00175mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 2,4-dichloro-6-(chloromethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-6-(chloromethyl)phenol(6333-33-1)
• EPA Substance Registry System: 2,4-dichloro-6-(chloromethyl)phenol(6333-33-1)

Safety Data

• Hazardous Substances Data: 6333-33-1(Hazardous Substances Data)

Usage

General Description

2,4-dichloro-6-(chloromethyl)phenol, also known as triclosan, is a synthetic, broad-spectrum antimicrobial agent commonly found in consumer products such as soaps, toothpaste, and hand sanitizers. It is effective against a wide range of bacteria and fungi, making it a popular ingredient in personal care and household products. However, concerns have been raised about its potential negative impact on human health and the environment, leading to increased scrutiny and regulatory restrictions in some regions. Studies have shown that triclosan can accumulate in the body and disrupt hormone regulation, potentially contributing to antibiotic resistance and ecological harm when washed down the drain. As a result, there is ongoing debate about the safety and necessity of triclosan in various products.

Upstream product

• 50-00-0 formaldehyd 
• 120-83-2 2,4-dichlorophenol 
• 7647-01-0 hydrogenchloride 
• 6641-02-7 3,5-dichloro-2-hydroxybenzyl alcohol 
• 90-60-8 3,5-dichlorosalicyclaldehyde 

Downstream Products

• 6641-02-7 3,5-dichloro-2-hydroxybenzyl alcohol 
• 90-60-8 3,5-dichlorosalicyclaldehyde 
• 873414-20-1 6,8-dichloro-2-phenyl-4H-benzo[1,3]dioxin 
• 89101-37-1 4,6,4'-trichloro-6'-chloromethyl-2,2'-methanediyl-di-phenol 
• 108122-97-0 3,5-dimethyl-2,2'-methanediyl-di-phenol 
• 51866-26-3 4-chloro-2-(5-chloro-2-hydroxy-benzyl)-6-(3,5-dichloro-2-hydroxy-benzyl)-phenol 
• 101792-45-4 1,4-bis-(3,5-dichloro-2-hydroxy-phenylmethanesulfonyl)-butane 
• 24299-63-6 <3.5-Dichlor-2-hydroxy-benzyl>-<2-(3-methyl-benzyl)-4.6-dimethyl-phenyl>-sulfon 
• 5419-53-4 4,6,4'-trichloro-2,2'-methanediyl-di-phenol 
• 17387-53-0 4,4',6'-trichloro-3,5-dimethyl-2,2'-methanediyl-di-phenol 

Relevant articles and documents

Modulation of electronic and redox properties in phenolate-rich cobalt(iii) complexes and their implications for catalytic proton reduction

We investigate the redox, spectroscopy and catalytic reactivity of new cobalt(iii) complexes based on phenolate-rich [N2O3] ligands. These complexes are described as [CoIII(LX)MeOH], where X indicates the presence of chloro (1), bromo (2), iodo (3), or tert-butyl (4) substituents in the 3rd and 5th positions of each phenolate ring. These substituents modulate the Co(iii) ← PheO- LMCT bands of the parent complexes with 1 (451) > 2 (453) > 3 (456) > 4 (468 nm) and the redox potentials involved with the Co(iii)/Co(ii) and ligand reduction and with the phenolate/phenoxyl oxidation processes. The influence of the substituents on the phenolate pendant arms was also observed on the kinetic parameters; 1 presented a rate constant of 1.0 × 10-3 s-1 whereas 4 showed a considerably slower rate (5.3 × 10-5 s-1). Species 1 and 4 are electrocatalysts towards proton reduction in the presence of weak acid in acetonitrile. A TON of 10.8 was observed for 1 after 3 h of bulk electrolysis at -2.20 VFc/Fc+ using a mercury pool as the working electrode. This journal is