63469-11-4

Basic information

• Product Name: P-NITROPHENYL PENTYL ETHER
• Synonyms: TIMTEC-BB SBB008318;P-NITROPHENYL PENTYL ETHER;P-PENTYLOXYNITROBENZENE;1-Nitro-4-(pentyloxy)benzene;Benzene, 1-nitro-4-pentyloxy;4-nitrophenyl pent-1-yl ether
• CAS NO: 63469-11-4
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.24
• Mol File: 63469-11-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 322.8°C at 760 mmHg
• Flash Point: 136.8°C
• Appearance: /
• Density: 1.093g/cm³
• Vapor Pressure: 0.000516mmHg at 25°C
• Refractive Index: 1.518
• CAS DataBase Reference: P-NITROPHENYL PENTYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROPHENYL PENTYL ETHER(63469-11-4)
• EPA Substance Registry System: P-NITROPHENYL PENTYL ETHER(63469-11-4)

Safety Data

• Hazardous Substances Data: 63469-11-4(Hazardous Substances Data)

Usage

Description

P-NITROPHENYL PENTYL ETHER is a chemical compound with the molecular formula C11H15NO3. It is an oily, colorless liquid that is insoluble in water and soluble in organic solvents.

Uses

Used in Organic Synthesis:
P-NITROPHENYL PENTYL ETHER is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions.
Used in Pharmaceutical Production:
P-NITROPHENYL PENTYL ETHER is used as an intermediate in the production of pharmaceuticals, contributing to the synthesis of various medications.
Used in Pesticide Production:
P-NITROPHENYL PENTYL ETHER is also used as an intermediate in the production of pesticides, playing a role in the creation of effective pest control agents.
Used as a Non-Volatile Solvent:
P-NITROPHENYL PENTYL ETHER is used as a non-volatile solvent in various applications, providing a stable and consistent medium for processes that require it.
Safety Precautions:
It is important to handle P-NITROPHENYL PENTYL ETHER with care, as it can be harmful if ingested or inhaled and may cause skin and eye irritation.

InChI:InChI=1/C11H15NO3/c1-2-3-4-9-15-11-7-5-10(6-8-11)12(13)14/h5-8H,2-4,9H2,1H3

Upstream product

• 100-02-7 4-nitro-phenol 
• 628-17-1 amyl iodide 
• 110-53-2 1-Bromopentane 
• 1124-31-8 potassium 4-nitrophenolate 
• 71-41-0 pentan-1-ol 
• 100-00-5 4-chlorobenzonitrile 
• 905718-45-8 [(4-nitrophenyl)(phenyl)iodonium trifluoromethanesulfonate] 

Downstream Products

• 39905-50-5 4-pentyloxyaniline 
• 19482-05-4 p-p-di-n-pentyloxyazoxybenzene 
• 19482-05-4 4,4'-bis(pentyloxy)azoxybenzene 
• 65937-76-0 4-n-methoxy-1-naphthylidene-p-n-pentyloxyaniline 
• 65937-75-9 4-n-ethoxy-1-naphthylidene-p-n-pentyloxyaniline 
• 65937-74-8 4-n-propyloxy-1-naphthylidene-p-n-pentyloxyaniline 
• 65937-77-1 4-n-pentyloxy-1-naphthylidene-p-n-pentyloxyaniline 
• 65937-73-7 4-n-butyloxy-1-naphthylidene-p-n-pentyloxyaniline 
• 14921-64-3 4-heptyloxybenzylidene-4'-pentyloxyaniline 
• 1390650-38-0 1,3-Bis(3-((4-pentyloxyphenylimino)methyl)phenoxy)-propan-2-ol 
• 1390650-39-1 1,3-Bis(4-((4-pentyloxyphenylimino)methyl)phenoxy)-propan-2-ol 

Relevant articles and documents

Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid

The YAP-TEAD transcriptional complex is responsible for the expression of genes that regulate cancer cell growth and proliferation. Dysregulation of the Hippo pathway due to overexpression of TEAD has been reported in a wide range of cancers. Inhibition of TEAD represses the expression of associated genes, demonstrating the value of this transcription factor for the development of novel anti-cancer therapies. We report herein the design, synthesis and biological evaluation of LM98, a flufenamic acid analogue. LM98 shows strong affinity to TEAD, inhibits its autopalmitoylation and reduces the YAP-TEAD transcriptional activity. Binding of LM98 to TEAD was supported by 19F-NMR studies while co-crystallization experiments confirmed that LM98 is anchored within the palmitic acid pocket of TEAD. LM98 reduces the expression of CTGF and Cyr61, inhibits MDA-MB-231 breast cancer cell migration and arrests cell cycling in the S phase during cell division.

Room temperature, metal-free arylation of aliphatic alcohols

Diaryliodonium salts are demonstrated as efficient arylating agents of aliphatic alcohols under metal-free conditions. The reaction proceeds at room temperature within 90 min to give alkyl aryl ethers in good to excellent yields. Aryl groups with electron

Liquid-crystalline polymorphism of 4-heptyloxybenzylidene-4′- alkyloxyanilines and their phase equilibrium with 4-octyloxyphenyl 4-nitrobenzoate

This paper describes the synthesis and liquid-crystalline properties of the homologous series of 4-heptyloxybenzylidene-4′-alkyloxyanilines (7-n). Six of them are presented for the first time. Based on the polarization microscopy (POM and TOA methods) and the calorimetric (DSC) measurements following polymorphism has been detected: nematic, smectic C and smectic I mesophases. The presence of these mesophases was confirmed by the miscibility method, using 4-octyloxyphenyl 4-nitrobenzoate and terephtal-bis (4-butyloaniline) as a mesophase references. Extraordinary results have been found in the mixtures of the investigated compounds with 4-octyloxyphenyl 4-nitrobenzoate; Induced smectic A has been observed, which is connected with very strong intermolecular interactions. Additionally destabilization of nematic and smectic C phases was visible.