63981-22-6 Usage
Description
3-(5-Nitrofurfurylideneamino)hydantoic acid is a novel derivative of 5-Nitro-2-furfural, characterized by its bactericidal properties. 3-(5-nitrofurfurylideneamino)hydantoic acid has been synthesized to enhance the antimicrobial activity and is related to Nitrofurantoin USP as a compound A.
Uses
Used in Pharmaceutical Industry:
3-(5-Nitrofurfurylideneamino)hydantoic acid is used as an antimicrobial agent for its bactericidal effects. It is particularly effective against a range of bacteria, making it a valuable component in the development of new antibiotics to combat bacterial infections.
Used in Medical Treatments:
3-(5-Nitrofurfurylideneamino)hydantoic acid is utilized as a therapeutic agent for treating bacterial infections. Its bactericidal nature allows it to target and eliminate harmful bacteria, contributing to the treatment and management of various infectious diseases.
Used in Research and Development:
3-(5-Nitrofurfurylideneamino)hydantoic acid serves as a key compound in scientific research and development within the field of microbiology and pharmaceuticals. It aids in the study of bacterial resistance mechanisms and the development of new strategies to overcome antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 63981-22-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,9,8 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 63981-22:
(7*6)+(6*3)+(5*9)+(4*8)+(3*1)+(2*2)+(1*2)=146
146 % 10 = 6
So 63981-22-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N4O6/c9-8(15)11(4-7(13)14)10-3-5-1-2-6(18-5)12(16)17/h1-3H,4H2,(H2,9,15)(H,13,14)/b10-3+
63981-22-6Relevant articles and documents
Assay of nitrofurantoin oral suspensions contaminated with 3-(5-nitrofurfurylideneamino)hydantoic acid
Juenge,Kreienbaum,Gurka
, p. 100 - 102 (1985)
A reversed-phase high-performance liquid chromatographic (HPLC) analysis of oral suspensions for nitrofurantoin (1) and 3-(5-nitrofurfurylideneamino)hydantoic acid (2), an impurity derived from 1, is presented. The concentration of the impurity ranged from 20 to 300 μg/mL in several lots of commercial oral suspensions. Conversion of 1 to 2 with citrate buffer, an excipient in the oral suspension, was achieved; selective hydantoin ring cleavage was accomplished in preference to the generally observed cleavage at the azomethine linkage. The hydantoic acid 2 was synthesized and identified by NMR, IR, TLC, and elemental analysis.
