64000-54-0

Basic information

• Product Name: Benzaldehyde, 3,4-bis(1-methylethoxy)-
• CAS NO: 64000-54-0
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 64000-54-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3,4-bis(1-methylethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3,4-bis(1-methylethoxy)-(64000-54-0)
• EPA Substance Registry System: Benzaldehyde, 3,4-bis(1-methylethoxy)-(64000-54-0)

Safety Data

• Hazardous Substances Data: 64000-54-0(Hazardous Substances Data)

Upstream product

• 75-30-9 2-iodo-propane 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 75-26-3 isopropyl bromide 

Downstream Products

• 1418016-40-6 C₃₀H₃₇NO₆ 
• 152340-67-5 (E)-3-(3,4-dihydroxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one 
• 487-52-5 butein 
• 1265221-69-9 C₄₁H₄₉NO₈ 
• 1265221-68-8 C₄₂H₅₁NO₁₀ 

Relevant articles and documents

Divergent Synthesis of Marine Natural Products Siphonodictyal B, Corallidictyals C/D, and Liphagal Based on the Early Presence of an Aldehyde Group Instead of a Late-Stage Introduction

An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals C/D, and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction.

Reactivity assessment of chalcones by a kinetic thiol assay

The electrophilic nature of chalcones (1,3-diphenylprop-2-en-1-ones) and many other α,β-unsaturated carbonyl compounds is crucial for their biological activity, which is often based on thiol-mediated regulation processes. To better predict their biological activity a simple screening assay for the assessment of the second-order rate constants (k2) in thia-Michael additions was developed. Hence, a clear structure-activity relationship of 16 differentially decorated hydroxy-alkoxychalcones upon addition of cysteamine could be established. Moreover, amongst other naturally occurring α,β-unsaturated carbonyl compounds k2 values for curcumin and cinnamaldehyde were gained while cinnamic acids or esters gave no or very slow reactions.

The first total synthesis of kynapcin-24 by palladium catalysis

The synthesis of kynapcin-24, which can be isolated from the Korean mushroom Polyozellus multiflex Murr, is achieved in 12% overall yield from commercially available 3,4-dihydroxybenzaldehyde by a route in which the longest linear sequence is only 14 step