64142-23-0

Basic information

• Product Name: 1-Butanone, 1-(4-hydroxy-3-methoxyphenyl)-
• Synonyms: 4-Butyryl-2-methoxy-phenol;4'-hydroxy-3'-methoxy-butyrophenone;butyrovanillone
• CAS NO: 64142-23-0
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 64142-23-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 54-55 °C
• Boiling Point: 185-195 °C(Press: 15 Torr)
• Density: 1.101±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Butanone, 1-(4-hydroxy-3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(4-hydroxy-3-methoxyphenyl)-(64142-23-0)
• EPA Substance Registry System: 1-Butanone, 1-(4-hydroxy-3-methoxyphenyl)-(64142-23-0)

Safety Data

• Hazardous Substances Data: 64142-23-0(Hazardous Substances Data)

Usage

Derivation

Derived from vanillin, the primary component of vanilla bean extract

Usage

Commonly used as a flavoring agent in the food and beverage industry, production of fragrances, pharmaceuticals, and as a chemical intermediate for various other compounds

Aroma

Pleasant and sweet

Popularity

Popular choice for adding flavor and fragrance to a wide range of products

Medicinal and therapeutic properties

Studied for its potential antioxidant and anti-inflammatory effects.

Upstream product

• 114515-48-9 1-(4-hydroxy-3-methoxy-phenyl)-butan-1-ol 
• 90-05-1 2-methoxy-phenol 
• 107-92-6 butyric acid 
• 141-75-3 butyryl chloride 
• 17386-89-9 4-Butyroylpyrocatechol 
• 74-88-4 methyl iodide 
• 881-68-5 vanillin acetate 

Downstream Products

• 134610-35-8 4'-hydroxy-3'-methoxy-5'-nitrobutyrophenone 
• 1447024-78-3 C₁₅H₂₀O₅ 

Relevant articles and documents

A convenient synthetic approach to dioncoquinone B and related compounds

A total synthesis of dioncoquinone B and related compounds, including ancistroquinones B, C and malvon A, is presented. The strategy is based on available reagents and can be used as a preparative synthesis of a number of natural and synthetic biologically active (3-alkyl)-2,7,8-di(tri)methoxy(hydroxy)-1,4-naphthoquinones.

Catechol derivatives

Catechol derivatives of the formula STR1 wherein Ra, Rb and Rc have the significance given herein, the ester and ether derivatives thereof which are hydrolyzable under physiological conditions and the pharmaceutically acceptable salts thereof are described and possess valuable pharmacological properties. In particular, they inhibit the enzyme catechol-O-methyltransferase (COMT), a soluble, magnesium-dependent enzyme which catalyses the transference of the methyl group of S-adensoylmethionine to a catechol substrate, whereby the corresponding methyl ethers are formed. Suitable substrates which can be O-methylated by COMT and which can thus be deactivated are, for example, extraneuornal catecholamines and exogeneously-administered therapeutically active substances having a catechol structure. Formula Ia above embraces not only compounds which form part of the invention, but also known compounds; the compounds which form part of the invention can be prepared according to known methods.