64433-61-0

Basic information

• Product Name: Phenanthridinium, 5-(phenylmethyl)-, bromide
• CAS NO: 64433-61-0
• Molecular Formula: C20H16N.Br
• Molecular Weight: 350.258
• Mol File: 64433-61-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenanthridinium, 5-(phenylmethyl)-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Phenanthridinium, 5-(phenylmethyl)-, bromide(64433-61-0)
• EPA Substance Registry System: Phenanthridinium, 5-(phenylmethyl)-, bromide(64433-61-0)

Safety Data

• Hazardous Substances Data: 64433-61-0(Hazardous Substances Data)

Upstream product

• 583-55-1 1-Bromo-2-iodobenzene 
• 75295-62-4 2′-bromo-[1,1′-biphenyl]-2-carbaldehyde 
• 100-46-9 benzylamine 
• 38559-35-2 3,10-dimethyl-5-deazaisoalloxazine 
• 229-87-8 phenanthridine 
• 100-39-0 benzyl bromide 

Downstream Products

• 26368-94-5 3-acetyl-N-benzylpyridinium bromide 
• 6516-53-6 N-benzyl-3-cyanopyridin-1-ium bromide 
• 38559-35-2 3,10-dimethyl-5-deazaisoalloxazine 
• 87861-97-0 5-(benzyl)phenanthridin-6(5H)-one 
• 87861-94-7 5-benzyl-5,6-dihydrophenanthridine 
• 1015-89-0 6(5H)-phenanthridinone 

Relevant articles and documents

Carbene-catalyzed aerobic oxidation of isoquinolinium salts: Efficient synthesis of isoquinolinones

A mild and environmentally friendly carbene-catalyzed aerobic oxidation of isoquinolinium salts was successfully realized. Accordingly, a diverse set of isoquinolinones and phenanthridinones was efficiently prepared in good to excellent yields. The mechanistic study indicates that the formation of an aza-Breslow intermediate is the crucial step in this transformation. This reaction features ambient air as the sole oxidant and oxygen source, a broad substrate scope, and excellent functional-group tolerance and proceeds under mild reaction conditions. Furthermore, a highly efficient synthesis of bioactive molecules and natural products including N-methylcrinasiadine, N-isopentylcrinasiadine, N-phenethylcrinasiadine, isoindolo[2,1-b]isoquinolin-5(7H)-one, PJ-34, rac-Gusanlung D, rosettacin, 8-oxopseudopalmatine and ilicifoline B was accomplished.

Marcus Theory of Hydride Transfer from an Anionic reduced Deazaflavin to NAD+ Analogues

Eighteen rate constants, kij for hydride transfer from the conjugate base of 1,5-dihydro-3,10-dimethyl-5-diazaisoalloxazine to a variety of pyridinium, quinolinium, phenanthridinium, and acridinium ions have been determined. (All the oxidizing agents can be regarded as analogues of NAD+.) The kij values span 7 powers of 10 and the corresponding equilibrium constants, Kij, span more than 13 powers of 10.For reactions with ΔG0 near zero, the kij values are close to those given by modified Marcus theory (ref 10).However, with more negative ΔG0 values, the observed kij increase more strogly than the calculated values.Agreement can be produced by making the standard free energy of precursor complex formation, symbolized WT +- here, to indicate that it applies to reactants of opposite charge, a linear function of ΔG0, and treating the slope and interrcept of the linear relation as adjustable parameters.The best fit is obtained with WT+-(in kJ*mol-1)=-9.4+0.11ΔG0.An avarage discrepancy between calculated and observed ln kij values of 0.5 is achieved, which is a good as the overall fit achieved for hydride transfer from neutral NADH analogues to NAD+ analogues (ref 10).The form and the parameterization of Wf are shown to be a physically reasonable approximation for reactions with ΔG00.These results strengthen the conclusion (ref 10) that a wide range of hydride transfer rates can be quantitavely understood without introducing high-energy metastable intermediates (radicals and radical ions).