64573-68-8

Basic information

• Product Name: Carbamothioic acid, cyclohexyl-, compd. with cyclohexanamine (1:1)
• CAS NO: 64573-68-8
• Molecular Formula: C7H13NOS.C6H13N
• Molecular Weight: 258.428
• Mol File: 64573-68-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamothioic acid, cyclohexyl-, compd. with cyclohexanamine (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamothioic acid, cyclohexyl-, compd. with cyclohexanamine (1:1)(64573-68-8)
• EPA Substance Registry System: Carbamothioic acid, cyclohexyl-, compd. with cyclohexanamine (1:1)(64573-68-8)

Safety Data

• Hazardous Substances Data: 64573-68-8(Hazardous Substances Data)

Upstream product

• 463-58-1 carbon oxide sulfide 
• 108-91-8 cyclohexylamine 
• 201230-82-2 carbon monoxide 

Downstream Products

• 463-58-1 carbon oxide sulfide 
• 108-91-8 cyclohexylamine 
• 2387-23-7 1,3-Dicyclohexylurea 

Relevant articles and documents

Practical synthesis of urea derivatives from primary amines, carbon monoxide, sulfur, and oxygen under mild conditions

A new and facile synthetic method for urea derivatives was developed under mild conditions, and contrasts with conventional preparation methods that need highly toxic reagents (phosgene) or severe reaction conditions. In our reaction system, N,N-dimethylformamide or dimethyl sulfoxide as solvent strongly accelerated the carbonylation of primary amines with sulfur under carbon monoxide (1 atm) at 20 °C to give the corresponding thiocarbamate salts. These salts were readily oxidized by molecular oxygen under similarly mild conditions to afford urea derivatives in good to excellent yields. This urea synthesis could also be applied to a new synthesis of aromatic ureas by use of 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethylformamide. Georg Thieme Verlag Stuttgart.

SYNTHESIS OF THIOCARBAMATE SALTS FROM AMINES, SULFUR, AND CARBON MONOXIDE

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