646-19-5 Usage
Description
1,7-Diaminoheptane, also known as 1,7-heptanediamine, is an organic compound with a seven-carbon chain and two amine groups attached to the first and seventh carbon atoms, respectively. It is a colorless liquid with a slight amine-like odor and is soluble in water. The presence of two amine groups in its structure makes it a versatile building block for the synthesis of various organic compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
1,7-Diaminoheptane is used as a key intermediate in the synthesis of 7-amino-1-guanidinooctane, which is a precursor for the development of therapeutic agents. 1,7-DIAMINOHEPTANE has potential applications in the treatment of various medical conditions, including cardiovascular diseases and neurological disorders.
Used in Biochemical Research:
1,7-Diaminoheptane is also used in the preparation of 1,7-diamino-trans-hept-3-ene, which serves as a deoxyhypusine synthase inhibitor. Deoxyhypusine synthase is an enzyme involved in the post-translational modification of proteins, and its inhibition can help researchers study the role of this enzyme in various biological processes and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 646-19-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 646-19:
(5*6)+(4*4)+(3*6)+(2*1)+(1*9)=75
75 % 10 = 5
So 646-19-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H18N2/c8-6-4-2-1-3-5-7-9/h1-9H2/p+2
646-19-5Relevant articles and documents
Photochemical Decarboxylative C(sp3)-X Coupling Facilitated by Weak Interaction of N-Heterocyclic Carbene
Chen, Kun-Quan,Wang, Zhi-Xiang,Chen, Xiang-Yu
supporting information, p. 8059 - 8064 (2020/11/02)
While N-hydroxyphthalimide (NHPI) ester has emerged as a powerful reagent as an alkyl radical source for a variety of C-C bond formations, the corresponding C(sp3)-N bond formation is still in its infancy. We demonstrate herein transition-metal-free decarboxylative C(sp3)-X bond formation enabled by the photochemical activity of the NHPI ester-NaI-NHC complex, giving primary C(sp3)-(N)phth, secondary C(sp3)-I, or tertiary C(sp3)-(meta C)phth coupling products. The primary C(sp3)-(N)phth coupling offers convenient access to primary amines.
Hydroboration/Amination of N-Trimethylsilyl Protected Olefinic Amines and Diolefins: Synthesis of Isomerically Pure Diamines
Kabalka, George W.,Wang, Zhe
, p. 2113 - 2118 (2007/10/02)
N-Trimethylsilyl protected olefinic amines and terminal diolefins were hydroborated with dimethylborane and the resulting organoboranes were treated with in situ generated chloramine or chloralkylamines to produce isomerically pure diamines or N-substituted diamines in good yields.