6460-87-3

Basic information

• Product Name: methyl 2-phenyl-3-hydroxyprop-2-enoate
• Synonyms: methyl 2-phenyl-3-hydroxyprop-2-enoate
• CAS NO: 6460-87-3
• Molecular Weight: 178.188
• Mol File: 6460-87-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-phenyl-3-hydroxyprop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-phenyl-3-hydroxyprop-2-enoate(6460-87-3)
• EPA Substance Registry System: methyl 2-phenyl-3-hydroxyprop-2-enoate(6460-87-3)

Safety Data

• Hazardous Substances Data: 6460-87-3(Hazardous Substances Data)

Upstream product

• 107-31-3 Methyl formate 
• 101-41-7 benzeneacetic acid methyl ester 
• 108471-63-2 (Z)-3-[(Morpholine-4-carbonyl)-amino]-2-phenyl-acrylic acid methyl ester 

Downstream Products

• 1188274-62-5 methyl (E)-2-phenyl-3-(p-toluenesulfonyloxy)prop-2-enoate 
• 1188274-63-6 methyl (Z)-2-phenyl-3-(p-toluenesulfonyloxy)prop-2-enoate 

Relevant articles and documents

General, Robust, and stereocomplementary preparation of α,β-disubstituted α,β-unsaturated esters

An (E)- and (Z)-stereocomplementary preparative method for α,β-disubstituted α,β-unsaturated esters Is performed via three general and robust reaction sequences: (i) TI-Claisen condensation (formylation) of esters to give α-formyl esters (12 examples, 60-99%), (II) (E)- and (Z)-stereocomplementary enol ρ-toluenesulfonylation (tosylation) using TsCI-N-methylimidazole (NMI)-Et3N and LiOH (24 examples, 82-99%), and (iii) stereoretentive Suzuki-Miyaura cross-coupling (18 examples, 64-96%).