64600-22-2

Basic information

• Product Name: Benzene, 1-(1-fluoroethenyl)-4-nitro-
• CAS NO: 64600-22-2
• Molecular Formula: C8H6FNO2
• Molecular Weight: 167.14
• Mol File: 64600-22-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-fluoroethenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-fluoroethenyl)-4-nitro-(64600-22-2)
• EPA Substance Registry System: Benzene, 1-(1-fluoroethenyl)-4-nitro-(64600-22-2)

Safety Data

• Hazardous Substances Data: 64600-22-2(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 75867-38-8 4-nitro-1-(trimethylsilylethynyl)benzene 
• 17763-80-3 para-nitrophenyl triflate 
• 100-02-7 4-nitro-phenol 
• 100-13-0 4-nitrostyrene 
• 636-98-6 p-nitrobenzene iodide 
• 257610-49-4 (α-Fluorovinyl)diphenylmethylsilane 
• 64600-30-2 1-(2-bromo-1-fluoroethyl)-4-nitrobenzene 

Relevant articles and documents

Fluoride ion-assisted cross-coupling reactions of (α-fluorovinyl)diphenylmethylsilane with aryl iodides catalyzed by Pd(0)/Cu(I) systems

The palladium-catalyzed cross-coupling reactions of (αfluorovinyl)diphenylmethylsilane with organic halides in the presence of Cu(I) halide afford good yields of α-fluorovinyl organic compounds.

Overcoming AlbD Protease Resistance and Improving Potency: Synthesis and Bioactivity of Antibacterial Albicidin Analogues with Amide Bond Isosteres

Albicidin is a potent antibacterial oligoaromatic peptide that is susceptible to the protease AlbD, a resistance factor. This potentially restricts the use of albicidin as a drug. To overcome this obstacle, we synthesized and evaluated six analogues with

Expedient synthesis of α-substituted fluoroethenes

A mild and efficient synthesis of 1-aryl-1-fluoroethenes from benzothiazolyl (aryl)fluoromethyl sulfones and paraformaldehyde, under DBU- or Cs2CO3-mediated conditions at room temperature, is described. A comparable diethyl fluoro(naphthalen-2-yl)methylphosphonate reagent does not react with paraformaldehyde under these mild conditions. The utility of the methodology for synthesis of terminal α-fluoroalkenes bearing electron-withdrawing functionalities is also shown.