649724-98-1

Basic information

• Product Name: Methanone, (2-hydroxy-6-methoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-
• CAS NO: 649724-98-1
• Molecular Formula: C25H27NO4
• Molecular Weight: 405.494
• Mol File: 649724-98-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methanone, (2-hydroxy-6-methoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-hydroxy-6-methoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(649724-98-1)
• EPA Substance Registry System: Methanone, (2-hydroxy-6-methoxy-1-naphthalenyl)[4-[2-(1-piperidinyl)ethoxy]phenyl]-(649724-98-1)

Safety Data

• Hazardous Substances Data: 649724-98-1(Hazardous Substances Data)

Upstream product

• 166975-76-4 4-(2-(piperidin-1-yl)ethoxy)benzoyl chloride 
• 5486-55-5 2,6-dimethoxylnaphthalene 
• 648905-80-0 (2,6-dimethoxynaphthalen-1-yl)-[4-(2-piperidin-1-ylethoxy)phenyl]methanone 

Downstream Products

• 648905-79-7 trifluoro-methanesulfonic acid 6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalen-2-yl ester 
• 736926-06-0 6-(4-methanesulfonylphenyl)-5-[4-(2-piperidin-1-ylethoxy)benzyl]naphthalen-2-ol 
• 648905-84-4 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methane 
• 648905-81-1 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone 
• 648905-83-3 [2-(4-methanesulfonylphenyl)-6-methoxynaphthalen-1-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanol 
• 874486-74-5 5-{hydroxy-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methyl}-6-(2,3,5-trifluoro-phenyl)-naphthalen-2-ol 
• 861930-75-8 [6-hydroxy-2-(2,3,5-trifluoro-phenyl)-naphthalen-1-yl]-[4-(2-piperidin-1-yl-ethoxy)phenyl]-methanone 
• 861931-20-6 5-{hydroxy-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methyl}-6-(2,3,5-trifluoro-phenyl)-naphthalen-2-ol 
• 651326-69-1 trifluoro-methanesulfonic acid 6-methanesulfonyloxy-1-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalen-2-yl ester 
• 861930-70-3 trifluoro-methanesulfonic acid 6-hydroxy-1-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalen-2-yl ester 

Relevant articles and documents

A selective estrogen receptor modulator for the treatment of hot flushes

A selective estrogen receptor modulator (SERM) for the potential treatment of hot flushes is described. (R)-(+)-7,9-difluoro-5-[4-(2-piperidin-1-ylethoxy) phenyl]-5H-6-oxachrysen-2-ol, LSN2120310, potently binds ERα and ERβ and is an antagonist in MCF-7 b

SELECTIVE ESTROGEN RECEPTOR MODULATORS

The present invention relates to a selective estrogen receptor modulators of formula I (I); or a pharmaceutical acid addition salt thereof; and of formula II (II); or a pharmaceutical salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.

SELECTIVE ESTROGEN RECEPTOR MODULATORS

The present invention relates to a selective estrogen receptor modulator of formula I: I; or a pharmaceutical acid addition salt thereof; useful, e.g., for treating endometriosis and uterine leiomyoma. X16065 PCT - -