65370-37-8Relevant articles and documents
Convenient entry to N-pyridinylureas with pharmaceutically privileged oxadiazole substituents via the acid-catalyzed C[sbnd]H activation of N-oxides
Geyl, Kirill,Baykov, Sergey,Tarasenko, Marina,Zelenkov, Lev E.,Matveevskaya, Vladislava,Boyarskiy, Vadim P.
supporting information, (2019/09/12)
Pyridine-N-oxides bearing a pharmacophoric oxadiazole moiety could be C[sbnd]H functionalized via the acid-catalyzed reaction with dialkylcyanamides, providing access to hitherto undescribed pyridine-2-yl substituted ureas, which have potential as “lead-l