6590-65-4

Basic information

• Product Name: N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&
• Synonyms: N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&
• CAS NO: 6590-65-4
• Molecular Formula: C₁₄H₁₃NO₃S
• Molecular Weight: 275.327
• Mol File: 6590-65-4.mol
• Article Data: 75

Chemical Properties

• Melting Point: 203-205 °C
• Boiling Point: 445.1°C at 760 mmHg
• Flash Point: 223°C
• Appearance: /
• Density: 1.333g/cm³
• Vapor Pressure: 4.05E-08mmHg at 25°C
• Refractive Index: 1.63
• PKA: 7.94±0.10(Predicted)
• CAS DataBase Reference: N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&(6590-65-4)
• EPA Substance Registry System: N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&(6590-65-4)

Safety Data

• Hazardous Substances Data: 6590-65-4(Hazardous Substances Data)

Usage

Description

N-(2-Formylphenyl)-4-methyl-benzenesulfonamide is a chemical compound with the molecular formula C14H13NO2S. It is a sulfonamide derivative, which is a class of organic compounds that contain a sulfonyl functional group attached to an amino group. This specific compound is characterized by a benzene ring with a formyl group at the 2-position and a methyl group at the 4-position. Sulfonamides are commonly used as antimicrobial agents and in the synthesis of pharmaceutical drugs. N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF&'s properties and potential applications are further determined through research and testing in various chemical and biological studies.

Uses

Used in Pharmaceutical Industry:
N-(2-Formylphenyl)-4-methyl-benzenesulfonamide is used as an intermediate in the synthesis of pharmaceutical drugs for its potential antimicrobial properties and its ability to be incorporated into various drug molecules.
Used in Chemical Research:
N-(2-FORMYLPHENYL)-4-METHYL-BENZENESULF& is used in chemical research to study the properties and reactions of sulfonamide derivatives, which can lead to the development of new compounds and applications in various fields.
Used in Antimicrobial Applications:
N-(2-Formylphenyl)-4-methyl-benzenesulfonamide may be used as an antimicrobial agent due to the general properties of sulfonamides, which can be effective against certain bacteria and other microorganisms.
(Note: The specific uses mentioned above are hypothetical and based on the general properties of sulfonamides. Further research and testing would be required to confirm the exact applications and efficacy of N-(2-Formylphenyl)-4-methyl-benzenesulfonamide.)

InChI:InChI=1/C14H13NO3S/c1-11-6-8-13(9-7-11)19(17,18)15-14-5-3-2-4-12(14)10-16/h2-10,15H,1H3

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 529-23-7 o-aminobenzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 
• 90312-02-0 N-(2-hydroxymethylphenyl)-4-methylbenzenesulfonamide 
• 50998-74-8 methyl N-tosylanthranilate 
• 134-20-3 2-carbomethoxyaniline 
• 111881-64-2 (2-hydroxymethyl-phenyl)-carbamic acid benzyl ester 
• 118-92-3 anthranilic acid 
• 552-89-6 2-nitro-benzaldehyde 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 5344-90-1 2-Aminobenzyl alcohol 
• 941-55-9 4-toluenesulfonyl azide 
• 5908-41-8 benzoyltrimethylsilane 

Downstream Products

• 182145-40-0 N-[2-(1-Hydroxyhept-6-enyl)phenyl]-4-methylbenzenesulfonamide 
• 77617-17-5 N-(2-tosylaminobenzylidene)aniline 
• 705256-10-6 N-[2-(benzyloxyimino-methyl)-phenyl]-4-methyl-benzenesulfonamide 

Relevant articles and documents

Phosphine-catalyzed [4+1] annulation of 2-tosylaminochalcones with allenoates: Synthesis of trans-2,3-disubstitued indolines

Phosphine-catalyzed [4+1] annulation of 2-tosylaminochalcones with allenoates has been achieved, giving trans-2,3-disubstitued indolines as major diastereoisomers in moderate to good yields.

A new route to 1,2,3-triazole fused benzooxazepine and benzodiazepine analogues through metal-free intramolecular azide-olefin oxidative cycloaddition

A collection of 1,2,3-triazole fused benzooxazepine and benzodiazepine analogues was prepared by one pot azide substitution and intramolecular azide-olefin oxidative cycloaddition sequence under metal-free conditions.

Transition metal-free approach to azafluoranthene scaffolds by aldol condensation/[1+2+3] annulation tandem reaction of isocyanoacetates with 8-(alkynyl)-1-naphthaldehydes

A transition metal-free aldol condensation/[1+2+3] annulation reaction of isocyanoacetates with 8-(alkynyl)-1-naphthaldehydes has been developed for the general synthesis of azafluoranthenes. This domino reaction enables successive formation of three new bonds and two rings from readily accessible starting materials in a single operation. Furthermore, this methodology can also be utilized to construct chromeno[4,3-c]pyridines and benzo[c][2,6]naphthyridines in moderate yields.

Cascade Skeletal Rearrangement of Gold Carbene Intermediates: Synthesis of Medium-Sized Pyrimidine-Fused Benzolactones

A gold-catalyzed cyclization/cascade skeletal rearrangement of o-cyanophenylalkynones with 3-amino-benzo[d]-isoxazoles has been developed, which provides an approach for synthesizing medium-sized benzolactones. Based on the experimental results, we postul

Iron-Catalyzed Electrophilic Amination of Sodium Sulfinates with Anthranils

A practical method for the synthesis of N-(2-carbonylaryl) benzenesulfonamides via an iron-catalyzed electrophilic amination of sodium sulfinates with anthranils is described. This redox-neutral transformation has high atom efficiency and is achieved under simple and mild reaction conditions. A wide range of anthranils and sodium sulfinates were compatible in this transformation. Moreover, the synthetic potential of this methodology was further demonstrated by the synthesis of various useful N-heterocycles and derivatives.