6654-36-0

Basic information

• Product Name: ADIPIC SEMIALDEHYDE METHYL ESTER
• Synonyms: ADIPIC SEMIALDEHYDE METHYL ESTER;METHYL 6-OXOHEXANOATE;Hexanoic acid, 6-oxo-, methyl ester;methyl 5-formylvalerate;5-Formylpentanoic acid methyl ester;6-Oxohexanoic acid methyl ester;Einecs 229-678-8;Methyl adipaldehydate
• CAS NO: 6654-36-0
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.17
• EINECS: 229-678-8
• Product Categories: Mixed Fatty Acids;Fatty Acid Derivatives & Lipids;Glycerols;Miscellaneous Reagents;Aldehydes;C7;Carbonyl Compounds
• Mol File: 6654-36-0.mol
• Article Data: 85

Chemical Properties

• Boiling Point: 83-86°C/1.5mmHg
• Flash Point: 71°C
• Appearance: Colorless/Liquid
• Density: 1 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.571mmHg at 25°C
• Refractive Index: 1.4391 (589.3 nm 20℃)
• Storage Temp.: −20°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: ADIPIC SEMIALDEHYDE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: ADIPIC SEMIALDEHYDE METHYL ESTER(6654-36-0)
• EPA Substance Registry System: ADIPIC SEMIALDEHYDE METHYL ESTER(6654-36-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 6654-36-0(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Oil

Uses

Methyl 6-Oxohexanoate (cas# 6654-36-0) is a compound useful in organic synthesis.

InChI:InChI=1/C7H12O3/c1-10-7(9)5-3-2-4-6-8/h6H,2-5H2,1H3

Upstream product

• 931-57-7 1-methoxy-cyclohex-1-ene 
• 67-56-1 methanol 
• 108-94-1 cyclohexanone 
• 110-83-8 cyclohexene 
• 15138-56-4 methyl 5-(1,3-dioxolan-2-yl)pentanoate 
• 541-43-5 barium formate 
• 186581-53-3 diazomethane 
• 818-57-5 Methyl 4-pentenoate 
• 201230-82-2 carbon monoxide 
• 16580-35-1 1-methoxy-1-hydroperoxycyclohexane 
• 107-18-6 allyl alcohol 
• 292638-85-8 acrylic acid methyl ester 
• 35444-44-1 methyl adipoyl chloride 
• 727737-13-5 methyl 6-morpholin-4-yl-6-oxohexanoate 

Downstream Products

• 25176-55-0 methyl 6,6-dimethoxyhexanoate 
• 627-93-0 hexanedioic acid dimethyl ester 
• 111998-08-4 methyl 6-cyclohexylidenehexanoate 
• 1745-17-1 methyl hept-6-enoate 
• 112375-42-5 methyl (6Z)-8-methylnon-6-enoate 
• 116265-56-6 1,5-Didesoxy-1,5-imino-N-<5-(methoxycarbonyl)pentyl>-L-fucit 
• 134765-49-4 (6S,7R)-6-Hydroxy-7-trimethylsilanyl-non-8-enoic acid methyl ester 
• 116265-51-1 2,3,4-Tri-O-benzoyl-1,5-didesoxy-1,5-imino-N-<5-(methoxycarbonyl)pentyl>-L-fucit 
• 194019-37-9 [N-(5-methyloxycarbonyl)pentyl]-(S-benzhydryl-L-cysteine) 
• 19641-63-5 (2R)-D-α-Aminosuberic acid 
• 4254-88-0 (2S)-L-α-Aminosuberic acid 
• 105-60-2 caprolactam 
• 373-04-6 6-aminocaproic amide 
• 2780-89-4 methyl 6-aminohexanoate hydrochloride 

Relevant articles and documents

Synthesis of Functionalized Aliphatic Acid Esters via the Generation of Alkyl Radicals from Silylperoxyacetals

We describe a catalytic method for the synthesis of a variety of functionalized aliphatic acid esters using silylperoxyacetals, which are versatile alkyl radical precursors with a terminal ester moiety. In the presence of an appropriate transition-metal catalyst, the in situ generation of alkyl radicals and the subsequent bond-forming process proceeds smoothly to afford synthetically valuable aliphatic acid derivatives. The present method can be applied to the efficient synthesis of a pharmaceutically important 1,1-diarylalkane motif. In addition, a novel strategy for the synthesis of structurally diverse hydroxy acid derivatives via a C?O bond formation process that utilizes TEMPO has been developed.

DIBALH: From known fundamental to an unusual reaction; Chemoselective partial reduction of tertiary amides in the presence of esters

This study presents a quick and reliable approach to the chemoselective partial reduction of tertiary amides to aldehydes in the presence of readily reducible ester groups using commercial DIBALH reagent. Moreover, the developed method was also extended to multi-functional molecules bearing ester moieties, which were successfully chemoselectively reduced to the corresponding aldehydes. This journal is

IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES

The disclosure provides ionizable amine lipids and salts thereof (e.g., pharmaceutically acceptable salts thereof) useful for the delivery of biologically active agents, for example delivering biologically active agents to cells to prepare engineered cells. The ionizable amine lipids disclosed herein are useful as ionizable lipids in the formulation of lipid nanoparticle-based compositions.