66737-07-3

Basic information

• Product Name: 1-(4-methoxycarbonylphenyl)-3-phenylpropynone
• Synonyms: 1-(4-methoxycarbonylphenyl)-3-phenylpropynone
• CAS NO: 66737-07-3
• Molecular Weight: 264.28
• Mol File: 66737-07-3.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxycarbonylphenyl)-3-phenylpropynone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxycarbonylphenyl)-3-phenylpropynone(66737-07-3)
• EPA Substance Registry System: 1-(4-methoxycarbonylphenyl)-3-phenylpropynone(66737-07-3)

Safety Data

• Hazardous Substances Data: 66737-07-3(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 619-44-3 methyl 4-iodobenzoate 
• 637-44-5 phenylpropyolic acid 
• 619-45-4 4-methoxycarbonyl aniline 
• 77726-96-6 methyl 4-(3,3-diethyltriaz-1-en-1-yl)benzoate 
• 536-74-3 phenylacetylene 
• 64-18-6 formic acid 
• 124-38-9 carbon dioxide 
• 108946-35-6 methyl 4-(1-hydroxy-3-phenylprop-2-yn-1-yl)benzoate 
• 1571-08-0 methyl 4-formylbenzoate 
• 1679-64-7 Monomethyl terephthalate 
• 3609-53-8 methyl 4-acetylbenzoate 
• 360789-45-3 4-Methoxycarbonyl-α-oxo-benzeneacetic acid 
• 100-52-7 benzaldehyde 

Downstream Products

• 86235-82-7 1-(4′-carbomethoxyphenyl)-3-phenyl-1,3-propanedione 
• 42497-80-3 methyl 4-(phenylethynyl)benzoate 

Relevant articles and documents

One-Pot Palladium-Catalyzed Carbonylative Sonogashira Coupling using Carbon Dioxide as Carbonyl Source

Carbonylation coupling reaction has emerged as a powerful and versatile strategy for the construction of carbonyl-containing compounds in modern synthetic chemistry over the past years. Carbon dioxide, a renewable one carbon molecule, has become one of the most attractive and promising alternative carbonyl sources due to its highly abundance, nontoxicity and stability in comparison with CO in recent years. However, in most cases, a two-chamber technique was generally necessary to allow the CO-producing and CO-consuming processes to perform successfully because of the complexities and incompatibility of reaction conditions, when carbon dioxide was utilized as carbonyl source. Herein, a practical one-pot protocol using carbon dioxide as the carbonyl source for the palladium-catalyzed carbonylative Sonogashira coupling has been established, providing an expedient and practical route to a wide range of functionalized alkynones and indoxyls under mild reaction conditions. By finding a suitable catalytic system, the method allowed the CO-generating and CO-consuming processes to proceed in one pot, wherein carbon monoxide was generated in situ from the reduction of carbon dioxide in the absence of any fluoride reagents. Simple and safe operation, readily available substrates, good functional group tolerance and mild reaction conditions are the features of the method.

Recyclable heterogeneous palladium-catalyzed carbonylative Sonogashira coupling under CO gas-free conditions

A convenient, efficient and practical heterogeneous palladium-catalyzed carbonylative Sonogashira coupling of aryl iodides with terminal alkynes under CO gas-free conditions has been developed by using an MCM-41-supported bidentate phosphine palladium ace

Rhodium-Catalyzed Intermolecular trans-Disilylation of Alkynones with Unactivated Disilanes

Disilylation of alkynes could provide rapid entry to synthetically useful 1,2-bissilyl-alkenes, but is currently limited to activated disilanes reacting in an intramolecular fashion. Reported herein is an efficient rhodium(I)-catalyzed intermolecular disi