6678-14-4

Basic information

• Product Name: 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE
• Synonyms: 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE;11BETA,17ALPHA,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 21-CAPRYLATE;HYDROCORTISONE 21-OCTANOATE;HYDROCORTISONE 21-CAPRYLATE;CORTISOL OCTANOATE;11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-octanoate;4-Pregnene-11β,17α,21-triol-3,20-dione 21-caprylate, Cortisol octanoate, Hydrocortisone 21-octanoate, 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-caprylate;Octanoic acid 11β,17-dihydroxy-3,20-dioxopregn-4-en-21-yl ester
• CAS NO: 6678-14-4
• Molecular Formula: C29H44O6
• Molecular Weight: 488.66
• EINECS: 229-717-9
• Mol File: 6678-14-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 632°C at 760 mmHg
• Flash Point: 201.4°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 1.25E-18mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: −20°C
• CAS DataBase Reference: 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE(6678-14-4)
• EPA Substance Registry System: 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE(6678-14-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 6678-14-4(Hazardous Substances Data)

Usage

Description

4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE, also known as Hydrocortisone 21-Octanoate, is a skin permeable fatty acid hydrocortisone derivative. It is a corticosteroid that exhibits anti-inflammatory, immunosuppressive, and vasoconstrictive properties. Its unique structure allows for enhanced penetration through the skin, making it a promising candidate for pharmaceutical applications.
Used in Pharmaceutical Industry:
4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE is used as a corticosteroid for its anti-inflammatory, immunosuppressive, and vasoconstrictive properties. It is particularly useful in the treatment of various skin conditions, such as eczema, dermatitis, and psoriasis, due to its enhanced skin permeability. Its ability to penetrate the skin more effectively than traditional corticosteroids allows for better therapeutic outcomes and reduced systemic side effects.

InChI:InChI=1/C29H44O6/c1-4-5-6-7-8-9-25(33)35-18-24(32)29(34)15-13-22-21-11-10-19-16-20(30)12-14-27(19,2)26(21)23(31)17-28(22,29)3/h16,21-23,26,31,34H,4-15,17-18H2,1-3H3/t21-,22-,23-,26+,27-,28-,29-/m0/s1