6681-13-6 Usage
Description
Hernandezine is a novel anticancer AMPK activator that has been identified as a major active constituent of Thalictrum Ranunculaceae. It is an alkaloid compound with unique chemical properties and potential therapeutic applications.
Uses
Used in Pharmaceutical Industry:
Hernandezine is used as an anticancer agent for its ability to activate AMPK, a protein kinase that plays a crucial role in regulating cellular energy homeostasis and metabolism. Its activation has been associated with the inhibition of tumor growth and the promotion of cell cycle arrest and apoptosis in cancer cells.
Additionally, Hernandezine may be used in combination with other chemotherapeutic agents to enhance their efficacy and overcome drug resistance in cancer treatment. Its unique mechanism of action and potential synergistic effects make it a promising candidate for further research and development in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 6681-13-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,8 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6681-13:
(6*6)+(5*6)+(4*8)+(3*1)+(2*1)+(1*3)=106
106 % 10 = 6
So 6681-13-6 is a valid CAS Registry Number.
6681-13-6Relevant articles and documents
Hernandezine salt and preparation method thereof
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, (2020/04/17)
The invention discloses a hernandezine salt prepared from hernandezine and an acid, wherein the acid is at least one of hydrochloric acid, hydrobromic acid, carbonic acid, sulfuric acid, phosphoric acid, nitric acid, maleic acid, fumaric acid, succinic acid, oxalic acid, trifluoroacetic acid, tartaric acid, ascorbic acid, N-benzoylglycine, L-pyroglutamic acid, L-proline, 2-hydroxyethyl sulfonic acid, acetic acid, benzoic acid, glycine, lysine, arginine, aspartic acid, gallic acid, lactic acid, whey acid, malic acid, citric acid, methanesulfonic acid, benzenesulfonic acid and p-toluenesulfonicacid. The halodiazine salt provided by the invention takes hanfangchin B as a raw material, the halodiazine is prepared through bromination, methoxylation and methylation reactions, the reaction yieldis high, intermediates and products are easy to purify, and the halodiazine can be used for industrial preparation of the halodiazine salt.
