66962-63-8

Basic information

• Product Name: C₅₂H₆₄N₆O₁₅
• Synonyms: C₅₂H₆₄N₆O₁₅
• CAS NO: 66962-63-8
• Molecular Weight: 1013.11
• Mol File: 66962-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₂H₆₄N₆O₁₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₂H₆₄N₆O₁₅(66962-63-8)
• EPA Substance Registry System: C₅₂H₆₄N₆O₁₅(66962-63-8)

Safety Data

• Hazardous Substances Data: 66962-63-8(Hazardous Substances Data)

Upstream product

• 2503-31-3 N-benzyloxycarbonyl-L-alanylglycine 
• 66962-55-8 1,2',6'-tri-N-(benzyloxycarbonyl)fortimicin B 
• 55779-06-1 fortimicin A 
• 54783-95-8 fortimicin B 
• 66962-56-9 1,2',6',2''-tetra-N-benzyloxycarbonyl-4-N-methyl-fortimicin A 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

Downstream Products

• 66962-82-1 (S)-2-Amino-N-[({(1S,2R,3R,4S,5S,6R)-4-amino-3-[(2R,3R,6S)-3-amino-6-(1-amino-ethyl)-tetrahydro-pyran-2-yloxy]-2,5-dihydroxy-6-methoxy-cyclohexyl}-methyl-carbamoyl)-methyl]-propionamide; hydrochloride 

Relevant articles and documents

4-N-acylfortimicins B and the preparation of fortimicin A from fortimicin B.

Selective 4-N-acylation of fortimicin B (2) has been accomplished by 4-N-acylation of 1,2',6'-tri-N-benzyloxycarbonylfortimicin B (4) followed by hydrogenolysis of the N-protecting benzyloxycarbonyl groups. In this manner, fortimicin B was converted into fortimicin A (1), and a series of 4-N-acylfortimicins B (3) was prepared for antibacterial assay. The key intermediate, 1,2',6'-tri-N-benzyloxycarbonylfortimicin B, was prepared either directly from fortimicin B or by converting fortimicin A into 1,2',6',2''-tetra-N-benzyloxycarbonylfortimicin A (6a), followed by selective hydrolysis of the 4-N-(N-benzyloxycarbonyl)glycyl group of the latter.