672310-73-5Relevant articles and documents
Catalytic Oxidative Coupling Cyclization for Construction of Benzofuroindolenines under Mild Reaction Conditions
Lin, Yuqi,Ye, Jinxiang,Zhang, Wenting,Gao, Yu,Chen, Haijun
supporting information, p. 432 - 435 (2018/12/13)
We describe iron-catalyzed oxidative coupling cyclization of tetrahydrocarbazoles or THβCs or THγCs to form benzofuroindolenines as fused polycyclic indoles. This mild, efficient and simple approach afforded a library of more than 52 complex compounds across a range of substrate classes with good to excellent yields. (Figure presented.).
Antimony (III) sulfate catalyzed one-pot synthesis of 2,3- disubstitutedindoles
Srinivasa,Mahadevan,Varma, P. Prabhakara,Sudhakara
experimental part, p. 1843 - 1853 (2010/02/28)
A novel one-pot Fischer indole synthesis approach has been developed by using antimony (III) sulfate as the catalyst. Good yields were obtained after reacting phenylhydrazines hydrochlorides and ketones in refluxing methanol. The exclusive formation of 2,3- disubstituted indoles was observed in the reaction of ethyl methyl ketone with phenylhydrazines. One-pot synthesis of indole-3-propanol using dihydropyran has also been described. The use of reusable antimony (III) sulfate as a catalyst makes this method both economically and environmentally friendly.
Fischer indole synthesis in bronsted acidic ionic liquids: A green, mild, and regiospecific reaction system
Xu, Dan-Qian,Yang, Wen-Long,Luo, Shu-Ping,Wang, Bing-Tao,Wu, Jian,Xu, Zhen-Yuan
, p. 1007 - 1012 (2008/03/12)
A novel one-pot Fischer indole synthesis approach has been developed by using Bronsted acidic ionic liquids as dual solvent-catalysts. Yields of 83-97 % were obtained after reaction in BMImHSO4 at 70-110°C in 0.5-6 h, and exclusive formation of 2,3-disubstituted indoles was observed in the reaction of alkyl methyl unsymmetrical ketones. The indoles produced could be conveniently separated from the reaction mixture without any volatile organic solvents, and the BMImHSO4 could be readily reused without efficiency loss after simple treatment involving only 1 equiv. of HCl for neutralization followed by filtration. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
