67815-57-0

Basic information

• Product Name: 1,3-Diiodotetrafluorobenzene
• Synonyms: 1,3-Diiodotetrafluorobenzene;1,2,3,5-Tetrafluoro-4,6-diiodobenzene
• CAS NO: 67815-57-0
• Molecular Formula: C₆F₄I₂
• Molecular Weight: 401.8667528
• Mol File: 67815-57-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 256.5°C at 760 mmHg
• Flash Point: 103.6°C
• Appearance: /
• Density: 2.671g/cm³
• Vapor Pressure: 0.0246mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 1,3-Diiodotetrafluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Diiodotetrafluorobenzene(67815-57-0)
• EPA Substance Registry System: 1,3-Diiodotetrafluorobenzene(67815-57-0)

Safety Data

• Hazardous Substances Data: 67815-57-0(Hazardous Substances Data)

Usage

Appearance

Colorless, crystalline solid

Solubility

Insoluble in water

Usage

Primarily used in organic synthesis as a building block for the preparation of various compounds

Chemical properties

Presence of iodine and fluorine in its structure gives it unique chemical properties

Applications

Useful in a variety of reactions in the pharmaceutical and chemical industries

Precursor

Used as a precursor for the synthesis of various biologically active molecules

Material development

Utilized in the development of new materials with specific properties

Safety

Should be handled with care due to its toxic and potentially harmful effects if not used properly

InChI:InChI=1/C6F4I2/c7-1-2(8)5(11)4(10)6(12)3(1)9

Upstream product

• 2367-82-0 1,2,3,5-tetrafluorobenzene 

Downstream Products

• 113705-13-8 1,3-bis((trimethylsilyl)ethynyl)tetrafluorobenzene 
• 13332-15-5 1,2,3,5-tetrafluoro-4-iodobenzene 
• 2367-82-0 1,2,3,5-tetrafluorobenzene 
• 27602-33-1 1-trimethylsilyl-2,3,4,6-tetrafluorobenzene 
• 113705-24-1 1,3-diethynyltetrafluorobenzene 
• 1430117-47-7 1,3-diiodotetrafluorobenzene*4,4',6,6'-tetramethyl-2,2'-bipyrimidine 
• 1430117-50-2 1,3-diiodotetrafluorobenzene*1,2,4,5-tetra(3-pyridyl)benzene 

Relevant articles and documents

In situ generation and trapping of aryllithium and arylpotassium species by halogen, sulfur, and carbon electrophiles

(Chemical Equation Presented) A general method has been developed for in situ trapping of arylmetal intermediates by halogen, sulfur, ketone, and aldehyde electrophiles affording the functionalization of the most acidic position in arene. Pentafluorobenzene, benzothiazole, and benzoxazole can be functionalized by using K3PO4 base. For less acidic arenes, tBuOLi base is required. Arenes with DMSO pKa values of 35 or less are reactive. 2009 American Chemical Society.

Synthesis of High Carbon Materials from Acetylenic Precursors. Preparation of Aromatic Monomers Bearing Multiple Ethynyl Groups

The synthesis of polyethynyl aromatics as starting materials for the preparation of highly cross-linked organic solids containing high atom fractions of carbon is described.Treatment of bromo- and iodoaromatic compounds with (trimethylsilyl)acetylene (TMSA) in the presence of palladium(O) and copper(I) in amine solvents yields (trimethylsilyl)ethynyl-substituted aromatics.The TMS protecting groups can be removed by hydrolysis with mild base.Compounds prepared by using this technique include 1,3-diethynylbenzene, 2,5-diethynylthiophene, 1,3-diethynyltetrafluorobenzene, 1,4-diethynyltetrafluorobenzene, 2-ethynylthiazole, 2,4-diethynylthiazole, 2,7-diethynylnaphthalene, hexakis((trimethylsilyl)ethynyl)benzene, tetraethynylthiophene, 2,5-bis((trimethylsilyl)ethynyl)-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, 2,5-diethynyl-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, 2,5-bis(4-(2-thienyl)butadiynyl)-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, and 2,5-bis-(4-(2-thienyl)butadiynyl)-3,4-diethynylthiophene.

THE EFFECT OF LEWIS ACIDS ON THE THALLATION OF POLYFLUOROARENES

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