68017-21-0

Basic information

• Product Name: 5-oxohexenoic acid benzyl ester
• Synonyms: 5-oxohexenoic acid benzyl ester
• CAS NO: 68017-21-0
• Molecular Weight: 220.268
• Mol File: 68017-21-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-oxohexenoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-oxohexenoic acid benzyl ester(68017-21-0)
• EPA Substance Registry System: 5-oxohexenoic acid benzyl ester(68017-21-0)

Safety Data

• Hazardous Substances Data: 68017-21-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 3128-06-1 5-ketohexanoic acid 
• 186581-53-3 diazomethane 
• 67852-85-1 glutaric acid chloride monobenzyl ester 
• 108-55-4 glutaric anhydride, 
• 54322-10-0 glutaric acid monobenzyl ester 
• 100-51-6 benzyl alcohol 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 87995-27-5 benzyl hex-5-enoate 
• 1120-72-5 2-Methylcyclopentanone 
• 2495-35-4 benzylacrylate 
• 67-64-1 acetone 

Downstream Products

• 136103-80-5 Benzyl 6,6-difluoro-5-methyl-5-hexenoate 
• 1029126-16-6 6-bromo-5-oxo-hexanoic acid benzyl ester 
• 1029126-05-3 2-amino-4-(3-benzyloxycarbonyl-propyl)-imidazole-1-carboxylic acid tert-butyl ester 
• 1309767-12-1 tert-butyl 4-(3-((benzyloxy)carbonyl)propyl)-2-((di-tert-butoxycarbonyl)amino)-imidazole-1-carboxylate 
• 57711-61-2 Benzyl-3-acetoxypropionat 

Relevant articles and documents

Synthesis method of 4-acetyl butyrate compound

The invention discloses a synthetic method of a 4-acetyl butyrate compound, and relates to the technical field of chemical synthesis, and the synthetic method comprises the following steps: taking acetone as a reaction solvent and a reactant to react with an acrylate compound under the catalytic action of tetrahydropyrrole; and after the reaction is finished, carrying out post-treatment on the reaction liquid to prepare the 4-acetyl butyrate compound. The method has the advantages of simple reaction system, environment friendliness, cheap and easily available raw materials, simple post-treatment operation, and no need of column chromatography purification, and is beneficial for industrial production.

Palladium/Copper-catalyzed Oxidation of Aliphatic Terminal Alkenes to Aldehydes Assisted by p-Benzoquinone

The development of an anti-Markovnikov Wacker-type oxidation for simple aliphatic alkenes is a significant challenge. Herein, a variety of aldehydes can be selectively obtained from various unbiased aliphatic terminal alkenes using PdCl2(MeCN)2/CuCl in the presence of p-benzoquinone (BQ) under mild reaction conditions. Isomerization of the terminal alkene to the internal alkene was suppressed via slow addition of the starting material to the reaction mixture. In addition to the Pd catalyst, CuCl and BQ were essential in order to obtain the anti-Markovnikov product with high selectivity. Terminal alkenes bearing a halogen substituent afforded their corresponding aldehydes with high anti-Markovnikov selectivity. The halogen acts as a directing group in the reaction. DFT calculations indicate that a μ-chloro Pd(II)?Cu(I) bimetallic species with BQ coordinated to Cu is the catalytically active species in the case of a terminal alkene without a directing group.

Inhibition of Acinetobacter baumannii biofilm formation on a methacrylate polymer containing a 2-aminoimidazole subunit

A polymeric composite containing a 2-aminoimidazole derivative was synthesized. It was found that this polymer was resistant to biofilm colonization by Acinetobacter baumannii, no leaching of the 2-aminoimidazole derivative was observed after 2 weeks of treatment with deionized water, and the resulting polymer was not hemolytic.