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68168-23-0

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68168-23-0 Usage

Description

Beta-Cyclodextrin hydrate, also known as β-Cyclodextrin (β-CD), is a macrocyclic oligosaccharide belonging to the cyclodextrin family. It is composed of seven D-glucose units connected via α(1→4) glycosidic bonds, forming a torus-shaped ring configuration with a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. This unique structure allows it to form inclusion complexes with various organic and inorganic compounds, making it a versatile molecule in pharmaceutical research and chemical applications.

Uses

Used in Pharmaceutical Research:
Beta-Cyclodextrin hydrate is used as a pharmaceutical intermediate for improving the aqueous solubility of various compounds, particularly those containing a phenyl group. Its ability to form inclusion complexes with these compounds enhances their solubility in water, which is crucial for drug delivery and absorption.
Used in Chemical Reagents:
As a chemical reagent, beta-Cyclodextrin hydrate is utilized in the formation of clathrates and for the production of water-soluble complexes with compounds like dansyl chloride. This application is particularly useful in the fluorescent labeling of proteins, which is an important technique in biochemistry and molecular biology.
Used in Drug Delivery Systems:
Beta-Cyclodextrin hydrate is employed in the development of novel drug delivery systems to enhance the bioavailability and therapeutic outcomes of various drugs. Its ability to form inclusion complexes with drugs can improve their stability, solubility, and controlled release, making it a valuable component in the design of advanced drug delivery systems.

Purification Methods

Recrystallise β-cyclodextrin from water and dry it for 12hours in a vacuum at 110o, or 24hours in a vacuum at 70o. The purity is assessed by TLC on cellulose containing a fluorescent indicator. [Taguchi, J Am Chem Soc 108 2705 1986, Tabushi et al. J Am Chem Soc 108 4514 1986, Orstam & Ross J Phys Chem 91 2739 1987.] [Beilstein 19 IV 6287, 19/12 V 801.]

Check Digit Verification of cas no

The CAS Registry Mumber 68168-23-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,1,6 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68168-23:
(7*6)+(6*8)+(5*1)+(4*6)+(3*8)+(2*2)+(1*3)=150
150 % 10 = 0
So 68168-23-0 is a valid CAS Registry Number.
InChI:InChI=1/C42H70O35.H2O/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51;/h8-63H,1-7H2;1H2

68168-23-0 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (A14529)  beta-Cyclodextrin hydrate   

  • 68168-23-0

  • 5g

  • 102.0CNY

  • Detail
  • Alfa Aesar

  • (A14529)  beta-Cyclodextrin hydrate   

  • 68168-23-0

  • 25g

  • 320.0CNY

  • Detail
  • Alfa Aesar

  • (A14529)  beta-Cyclodextrin hydrate   

  • 68168-23-0

  • 100g

  • 886.0CNY

  • Detail
  • Aldrich

  • (856088)  β-Cyclodextrinhydrate  99%

  • 68168-23-0

  • 856088-5G

  • 190.71CNY

  • Detail
  • Aldrich

  • (856088)  β-Cyclodextrinhydrate  99%

  • 68168-23-0

  • 856088-25G

  • 625.95CNY

  • Detail
  • Aldrich

  • (856088)  β-Cyclodextrinhydrate  99%

  • 68168-23-0

  • 856088-100G

  • 1,689.48CNY

  • Detail

68168-23-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name beta-Cyclodextrin hydrate

1.2 Other means of identification

Product number -
Other names β-Cyclodextrin hydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:68168-23-0 SDS

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